No. 1 (2018)

The aim of the research is to improve the methods of mining analysis based on electromagnetic fields and to develop energy-saving technologies and devices for processing rocks.
Tasks of the research:
substantiation of the dependence of electromagnetic fields on the process of primary and secondary processing of materials;
improvement of methods for obtaining high-quality cement and ultrapure materials by dividing them on the basis of electromagnetic fields;
development of a multifunctional control device for technological processes of grinding, separation, enrichment and obtaining ecologically clean composite materials;
the development of a control system for an electromagnetic field device to reduce the energy consumption of technological processes for the enrichment of materials.
Object of the research are devices for processing technogenic and mineral resources in industrial enterprises, leading to energy and resource saving.
Scientific novelty of the research is as following:
the dependences of the interaction of charged particles in the electro magnetic field for the separation of the necessary elements from composite materials are justified;
methods for constructing equia-energy surfaces for grinding composite materials on the basis of the properties of the electro-magnetic field have been improved;
improved methods for obtaining high-quality cement and ultra-pure materials by means of the device, by enriching materials based on electromagnetic fields;
a multifunctional control device has been developed to improve the technological process of obtaining environmentally friendly materials, their grinding, separation and enrichment.
The structure and volume of the research work. The thesis consists of an introduction, four chapters, a conclusion, a list of literature, and applications. The volume of the thesis is 114 pages.

The purpose of the study is to study the functional state of the cardiovascular system (CS) and to develop clinical-prognostic criteria for the risk of various outcomes of labor in pregnant women with valvular and inflammatory diseases of the heart.
Scientific novelty is in the following:
For the first time it was found out that the disadaptive changes of systemic / central hemodynamics and of electrical properties of the myocardium in the II-III trimester of gestation against anemia, FM and RHM, aggravated when pregnancy is repeated more than three times - multigravida (MG), underlie the development of pregnancy complications and childbirth;
for the first time it was determined that FM in pregnant women in the II-III trimesters of gestation is accompanied by the development of clinical signs of heart failure (mainly I-II functional class), electrical instability of the myocardium and cardiac conduction abnormalities;
it was just discovered that the severity of characteristic hemodynamic changes under RHD with a predominance of mitral valve insufficiency (MVI), a decrease in ejection fraction, an increase in mean pulmonary artery pressure, and the appearance of fluid in the pericardium cavity arc associated with gestational age and the presence of an active rheumatic process;
for the first time it was revealed that the electrical instability of the myocardium (supraventricular arrhythmia, ventricular arrhythmia) and cardiac conduction disorder (prolongation of PQ, QRS) is the leading symptom complex in the active rheumatic process of pregnant women in the II-III trimesters of gestation;
it was found out that FC III heart failure of pregnant women with FM and RHD is a risk factor for the development of gestosis, fetoplacental insufficiency and a low assessment of the Apgar state for newborns. On the other hand, MG increases the risk of development of weakness of labor;
based on the method of normalization of intensive indicators of clinical and hemodynamic data, a new integral approach to the risk assessment of complications of pregnancy and childbirth in pregnant women with FM and RHD was developed.

Actuality and relevance of the topic. The leguminous grain crops are necessary nutritional product for human body due to its reach protein, fat and carbohydratecontents. Therefore, development and implementation of effective combating measures against harmful pests for leguminous grain crops on the basis of the study of the species variety, biological and ecological features, distribution and harmfulness of damage for leguminous crops is one of the most important tasks.
The purpose of the research is development of scientific based effective combating measures against pestsof leguminous grain cropsand the study of their species varieties, biological features, distribution and damagesfor leguminous crops.
The scientific novelties of the researchare follows:
During the last 50 years, there had been revision the types of pests of leguminous grain crops in the country. The identified pests have been classified for basic, secondary and economically insignificant species. The identified pests are classified as main, secondary and economically insignificant types. There have been investigated the biological features and level of damage of main pests. There have been identified the species of natural entomophagies, which met in leguminous grain crops biocenosis and their importance in reducing the number of pests. Biological and chemical means for combating against dominant pests have been developed and determined their biological and economic efficiency. There had been examined a new technology of insecticide using against pests and inculcated into practice.

The aim of research work. The aim of research work is to study plants which belong to cauliflower family and on the basis of these investigations to select promising sorts, identify proper period of sawing and introducing them.
The scientific novelty of the study is as follows:
First time observed and studied the varieties of lettuce and leaf turnip groups and successfully selected promising varieties which arc proper to the climatic conditions of our country and these varieties were selected as basic source;
Created early maturing, high yielding «Gulshod» and «Darmon» promising varieties of leaf turnip which arc appropriate to our climatic conditions;
In order to recieve high yield determined favourable spring and summer periods of sawing;
The connection of planting terms of the following crop to the chemical content of root and leaves were scientifically proved, moreover improved the planting technology of newly selected varieties;

The aim of the research work is to select weakly sprouted cherry rootstocks and to provide a scientific foundation for the effective technology of grafting rootstocks when growing sparse seedlings for the establishment of intensive industrial gardens.
Scientific novelty of the research work is expressed in the followings: for the first time introduced from abroad the rootstocks of cherries CAB 6P, Maxma Delbard-14, Colt, Krymsky-5 and VSL-2 and determined their growth force in the soil-climatic conditions of the republic;
the methods of intensive breeding of new rootstocks of cherry CAB 6P, cherry Shubinka, Colt, Krimsky-5 and VSL-2 from green cutting have been worked out;
a high correlation between the degree of soil moisture during the period of grafting (r = 0.97), the time of grafting (r = 0.93), and the survival of the eyepieces have been determined;
the technology of cultivation of weakly saplings of a sweet cherry with use of intermediate (intercalary) inserts is developed.

The urgency and relevance of the dissertation theme. It is important to meet the population’ demand for various vegetables and their primary and deep processing products. It could be overcome through the development of vegetable growing sector, which is a one of the main directions of agriculture. For this purpose, it is desirable to develop the sweet pepper scientifically-based cultivation agrotechnology and its introduction in the dchkans and other farms.
The object of the researches arc 28 sweet pepper variety samples, 10 F hybrids and their such parts as; plants, fruits, roots, stems and leaves.

The research goal is development of hydraulic design method for bilateral transverse dams, installed symmetrically on floodplain, with the consideration of channel and floodplain flow and varying roughness of channel and floodplain.
The scientific novelty of the research consists of the following:
design methods for damming, contraction coefficient over area, vortex zone lengths under bylatcral contraction of floodplain flow by blank transverse dams have been improved, taking into consideration the inteaction of floodplain and channel flows;
design method for velocity determination in contracted section have been improved for symetrieal contraction by floodplain dams, taking into consideration the dam installation angle and contraction coefficient for discharge;
design method for velocity field have been improved for contraction area under symmetrial flow contraction by floodplain transverse blank dams, considering uneven velocity distribution, longitudinal and transverse depth changes;
contracted section flow spreading and vortex zone length design parameters have been developed, with the account of floodplain and channel flow interaction, similar and varying roughnesses for floodplain and channel.
Conclusions
On the basis of conducted research for PhD dissertation named «Patterns of bilateral symmetric obstruction of floodplain flow by transverse blank dikes» the following conclusions have been presented:
1. The versatility of velocity fields at the interaction zone of floodplain and channel flows have been justified experimentally, width change patterns of this zones have been set for rivers with symmetrical floodplains. As a result, the compliance of theoretical and experimental studies have been justified.
2. Bilateral symmetric floodplain flow contraction by transverse dams result in intense change of natural regime of rivers, both in floodplain and channel, and generation of upstream vortex zones, contraction and spreading zones, hydraulically homogeneous zones form in areas of contraction and spreading: weakly disturbed core, adjacent flow, intense turbulent mixing, interaction zone. The research results allow predicting scour zones and soundly set the intervals between floodplain dams.
3. Unlike existing solutions based on mean velocities in contracted section, solution of hydraulic flow parameters, such as channel velocity Upo, and floodplain velocity U,l0, maximal velocity in floodplain Umo and at dam head arc given with the consideration of uneven velocity distribution. This allowed for drawing attention at scour depth increase to 10% - 30% at floodplain dam heads.
4. It has been experimentally established, that the increase of the extent of contraction by discharge 0q, dam installation angle ад, result in the decrease of spatial contraction coefficient £nr. Besides, their decrease intensity is 0,09 when dam end points downstream, and it equals 0,34, when dam end points upstream. Also analytical relationships have been proposed for determination of £np. These analytical relationships allow for choosing the optimum alternative for installation of bilateral floodplain dams.
5. It has been experimentally proven, that usage of A.M.Latishenkov’s graphical and analytical relationships is correct for calculation of velocity increase coefficient for channel part of contracted section PP. As a result the necessity to consider the angle <p between flow axes and velocity vector have been justified for designing river flow contraction by bilateral transverse dams.
6. In contrast to the existing solutions, the velocity field design method has been developed for contraction area of flow, symmetrically constrained by transverse floodplain dams with the account of longitudinal and transverse depth changes, uneven distribution of velocity in the zone of weakly disturbed core, existence of two turbulent mixing zones and interaction zone between channel and floodplain flows. The developed design method allows to protect river banks with bilateral transverse dams from scouring.
7. Using the main states of turbulent flow theory the following was developed theoretically: calculation method for velocities at channel Up, velocity at floodplains Unn,Um, reverse flows UH, spreading area length Le for cases of symmetrical contraction by transverse dams, when floodplain roughnesses differ пЛ1фп„„ and when they arc equal nM=n,,„. This resulted in possibility to develop plane schematic of flow regulation by bilateral transverse dams for symmetrical and asymmetrical flow spreading conditions.
8. The main results of the work underlined the recommendations, which were applied in industry for works on Amudarya river right and left bank protection and regulation from erosion at Turtkul, Ellikqala, Bcruni, Honka, Bogot and Urgench regions with annual economical efficiency of 80 million sum.

The aim of the work is to improve the system of integrated use of modem herbicides in the effective protection of winter wheat from weeds, the integrated of agro-technology of cultivation with high quality and quantity of grain yield.
Scientific novelty of the research worlds as follows:
for the first time, the system of protection of winter wheat after harvesting has been improved and in the phase of tillering against annual and perennial spikelet weed, as well as dicotyledonous weeds;
the most harmful species of weeds of winter wheat are identified and the herbicides used are grouped, species and quantities of weeds were determined, as well as the degree of their infection in grain fields in the Samarkand and Andijan regions;
the influence of herbicides «Derbi 175 SC, 17,5%»; «Starane 200, 20%» and «Everest 70%» on the quality of grain and on the formation of the root and aboveground parts of winter wheat;
the order integrated use of herbicides «Derbi 175 SC, 17,5%»; «Nokdaun maks 74,8%» during vegetation and after the growing season of winter wheat has been developed, taking into account of weeds and their harmfulness.

The aim of research work is synthesis of fluorinated polydentant ligands and their complexes with ions of Ni(II) and Cu(II), and determination of structures and properties.
Scientific novelty of the research is as follows:
The new 27 organic ligands and 44 intercomplex compounds on their base were synthesized for the first time;
single crystals of 6 ligands and 4 complexes were grown, their molecular and crystal structures were determined;
method of synthesis of fluorinated P-diketones by Lil I was developed for the first time;
systematic data about regio-oriented reactions of fluorinated 1,3-diketones with acylhydrasines and structural factors for obtaining some individual regioisomers were determined;
it was determined that central ion of 3d-metals in chelat compounds and double deprotonated residues of ligands form five and six-membered metallocycles;
formation of a d-n-dative bound between d-electrons of nickel and cupper atoms with я-orbitals of a monodentant Py ligand was proved.

The aim of research work is to convey the transformation of the categories of beauty and excited in the aesthetic teaching of Immanuel Kant from a scientifically philosophical point of view.
The scientific novelty of the research is as follows:
It has been revealed that aesthetic pleasure based on art is based on refined, pure beauty and excited. It is also based on a philosophical-aesthetic and phenomenological approach to the stabilization and management of axiological, psychological, self-awareness, interpersonal and institutional relationships;
Immanuel Kant’s teachings have been ethically-aesthctically characterized by such factors as the impartiality, non-conformity and generality of beauty and excited mcgacatcgoryes;
It was discovered that the categories of beauty and glory in the aesthetic teaching of Immanuel Kant were transformed indirectly by the Oriental scientific heritage, and revealed the common aspects of philosophical ideas with east thinkers;
Immanuel Kant has developed a moral and aesthetic basis for creating immunity for non-multidimcnsional threats in the form of «mass culture» on the basis of pure beauty and majesty in the aesthetics of Kant.

The aim of the research work is to explain the rule of the development of civil society in Uzbekistan and changes in social consciousness.
The scientific novelty of the research is as follows:
based on the dialectical linkages of civil society development and the forms of social consciousness (national and ethnic) in Uzbekistan;
the essence and functional dependence of social and economic consciousness is explained by sociological, regulatory, and apodictive characteristics of subjective and objective factors;
the emergence of a new system of values that reflects the new dimensions of the subjective factor in the development of civil society in Uzbekistan and the emergence of new moral values that reflect universal and democratic values are based on philosophical reasoning that the formation of a new world outlook based on modernization and globalization in social consciousness;
in the context of the development of civil society in Uzbekistan, it has been revealed that the social consciousness has the ability to effectively influence and reflect on the nature of relative independence and social reality;
it is scientifically justified that the process of integration, innovation and its creative features in Uzbekistan as a result of modernization.

The aim of the research work includes the complete inventory of the flora of the Malguzar ridge and determination of its phytogeographical position as an independent region of the Kuhistan district of the Central Asian Mountain province.
The scientific novelty of the research is as follows: for the first time, the actual checklist of the flora of the the Malguzar ridge has been compiled, it includes 1255 species of 465 genera and 84 families; Two new records for the flora of Uzbekistan, two new records for the flora of Pamir-Alay have been found, and 56 new findings have been detected for the flora of the Malguzar ridge; in the flora, life forms of species which are belonging to Classes of the Mountainous Central Asia and also Ancient Mediterranean Areas and hemicryptophytes have been detemined; it was proved that is the role as independent phytogeographical region in the flora of Kuhistan district of Mountainous Central Asia province of Malguzar ridge and also the borders between the Kuhistan and Nuratau districts has been detemined; locations of 24 rare and endemic species were found and maps that reflects their distribution were created using GIS;

The aim of the research work is to conduct comprehensive analysis of the ecological situation and its consequences for Uzbekistan in the second half of the XX century - beginning of XXI century.
The scientific novelty of the research work is based on the following:
the essence of the irrational and contradictive to the laws of nature use of natural resources and disposition and development of production forces in the Soviet period, which resulted in a violation of the balance of «nature-population-national economy», was researched;
it is proved that under the conditions of administrative bureaucracy, a disdainful attitude to the problems of social ecology resulted in a decrease of the standard of life and health of the population, jeopardized its gene pool;
the global, regional, national and local features of the environmental threat in the Republic of Uzbekistan are shown on the example of climate change processes, Aral and Aral Sea problems, external (trans boundary) and internal problems of the use of natural resources and the environment;
the essence of strategic directions and the organizational and legal bases of environmental policy that led to the transformational processes in this sphere during the years of independence is revealed on the basis of the system approach;
it is justified that on the basis of the principles of sustainable development the symbiosis of ecological, social and economic tasks served to create conditions for raising living standards and health of the population, stabilizing ecosystems in the zones of the republic under increased environmental threat; the priority tasks of strengthening the foundations of sustainable development in the situation of high population growth and its needs are also identified.

Subject of research: 102 patients (204 eyes) with hypertonic retinopathy elderly and senile age.
Purpose of work: Study efficiency a biorcgulating therapy on clinicfunctional condition of the organ of the vision and quality to life patient with hypertonic retinopathy in elderly and senile age and its clinic-patogynetics motivation.
Methods of research: questionnaire, clinic-ophthalmologic, instrumental, biochemical, statistical.
The results obtained and their novelty: is a rcvcalled ophthalmologic criterion, reflecting quality to life and efficiency of the treatment sick hypertonic retinopathy. The clinic-patogynetics is motivated efficiency of the connection Cortexin in standard hypotensive therapy hypertonic retinopathy, to account of increasing of the quip of the vision on 22,4% (R<0,05), expansions of the field of vision on 23% (R<0,05), improvements гемодинамики in CAR on 19,65% and in CVR on 23,45%, reconstruction SEX-AOS, NO-crgichic of the systems in SZH, increasing quality visions and quality to life on 43,6%.
Practical value: Designed short questionnaire on quality of life, for subjective estimation visual function, will help early revealed, preventive maintenance and efficiency of the treatment of the complications arterial hypertension on organ of the vision. Cut-in Cortexin in complex treatment sick elderly and senile age will allow raising efficiency on therapy hypertonic retinopathy in dispensary- policlinic condition or on house.
Degree of embed and economic efficiency: Proposed in thesis ways diagnostics, treatments, clinic-instrumental studies hemodynamic and functional activity of the visual analyzer under hypertonic retinopathy beside person’s elderly and senile age arc introduced in scholastic process of the pulpit to ophthalmology, to cardiology and gerontology Tashkent Institute of Improvement of Physicins Experiences, in practical activity ophthalmologic and gerontology cabinet central polyclinic №2 .
Field of application: ophthalmology, cardiology, gerontology.

Topicality and relevance of the theme of the dissertation. In Uzbekistan, using of solar energy (SE) is relevant, like to ensure energy security, and to improve the social and living conditions of the population. One of the most prepared area for large-scale using of solar cells in Uzbekistan is the system of hot water supply. For further expand the scale of the using of SE in this area in the first stage, it is necessary to have scientifically grounded information on their specific heat output and other technical, economic and environmental indicators.
The aim of the research is to development solutions for increasing the efficiency of using flat-plate solar collector (FSC)s in hot water supply systems (HWSS), optimizing their main thermal and engineering parameters, modeling the processes of thermal transformation of SE in them.
The scientific novelty of the research consists of following: - for the first time an approximate expression was found for determining the effective reduced coefficient of heat losses of the LAHP; - for the first time proposed and used in the calculation of a non-contact method for determining the average working temperature of LAHP; - proposed and implemented the methodology of complex optimization of the intertubular distance of sheet-paped LAHP.

The aim of research work is to synthesize new compounds based on ferrocene and methylolurea, to identify their biostimulating activity for plants, to develop commodity codes for newly synthesized biostimulators based on chemical composition and to introduce them into practice.
The object of research work was ferrocene, monomethylolurea, dimethylolthiourea and their derivatives.
The scientific novelty of research work is as follows:
new biologically active compounds based on ferrocene and methylolurea as well as their derivatives were synthesized for the first time; the formation of the derivatives of p-ferrocenylphenol, m-ferrocenylbenzoic acid with methylolurea and methylene dicarene as a result of the diazotization reaction in various solvents has been proved;
chemical compositions and physical properties of biologically active substances containing derivatives of ferrocene and methylolurea are determined; The biological activity of synthesized compounds, their influence on the germination of cotton seeds, the growth and development of cotton and its yield have been proved.
Introduction of research results. Based on the scientific results of the study of synthesized biologically active compounds based on ferrocene and methylolurea:
in 2012-2016 years. In Andijan and Fergana provinces, the technology of using the ADUMAKH biostimulator synthesized on the basis of ferrocene and methylolurea has been introduced on a total area of 100 hectares (certificate of the Ministry of Agriculture and Water Resources of the Republic of Uzbekistan dated December 27, 2017 №07 / 23-1126). At the same time, from every hectare of the area treated with the biostimulator, an additional 3-5 centners of yield was obtained. According to the commodity nomenclature of foreign economic activity, a commodity code has been developed for ferrocene and its derivatives 2942 00 000 1, for nitrogencontaining ferrocene derivatives 2942 00 000 2 and introduced into the practice of the state customs service (certificate of the State Customs Committee of the Republic of Uzbekistan dated Yanuar 06, 2018 №1/16-8). As a result, it became possible to classify biologically active compounds containing ferrocene and nitrogen.

The aim of the research work. The aim of the research is to develop the modification algorithms for calculating estimates by using the elements of fuzzy sets theory in Data Mining.
The scientific novelty of the research work is as follows:
the methods and algorithms for determining optimal values of threshold parameters and the length of voting sets of models of the algorithms for calculating estimates have been developed;
the algorithms for determining the optimal values of the membership functions parameters and threshold parameters using the genetic algorithm has been developed;
the eight-step modified model of the algorithms for calculating estimates based on the elements of the fuzzy sets theory has been developed;
the approach for determining the relationship between classes for modifying partial precedence algorithms has been developed.

The aim of the research work is the development and improvement of mathematical models, computational algorithms and computer models for studying the regulatory mechanisms of the interaction of skin epidermal cells.
The scientific novelty of the research work is as follows:
the biological models that describe the interrelationships of the dividing, differentiating, fulfilling specific functions of skin epidermal cells were improved;
the system of equations for the regulatory mechanisms of skin epidermal cells based on biological models was developed taking into account the spatiotemporal organization;
the mathematical model of interaction of regulatory mechanisms of skin epidermal cells was created on the basis of a system of functional-differential equations with stumbling arguments;
the computational methods for mathematical models of regulatory mechanisms of skin epidermis were developed, taking into account the time of back action;
the software for computing experiments intended for solving medical problems in the field of construction of models of the interconnected processes of regulatory mechanisms of skin epidermal cells was created.

The urgency and relevance of the theme of dissertation topic. In the world, modem epidemiological data of recurrent aphthous stomatitis (RAS) indicate widespread of the disease, and its frequency rate established from 35.0 to 60.0%. According to WHO, causes of multiple etiologic recurrent aphthous stomatitis, particularly, depends on various factors such as microclimate changes, food system failure of human body, and other issues, which lead to growth of disease, considerable difficulties in its treatment and its low efficiency and create the problems of setting a timely diagnosis.
The aim of the research work:
Improvement of tactics for the treatment of recurrent aphthous stomatitis with the use of ozone therapy.
The scientific novelty of the research work is as follow:
with different severity of RAS in the oral fluid and blood serum, positive effect regarding therapy sequence during complex multifactorial analysis of relationship between lipid peroxidation and antioxidant system components was demonstrated;
it is evident that the inclusion of systemic and local ozone therapy in complex therapy of RAS leads to an increase in active and decrease passive mechanisms of modulation of blood flow in the sites of erosive and ulcerative lesions in RAS, normalization of microcirculation and acceleration of reparative processes on the mucous membranes of the oral cavity;
complex ozone therapy in RAS based on the normalization of microbiocoenosis of the oral cavity and intestines, prolonging the period of remission and improving the efficacy of long-term treatment outcomes;
it was proved that stimulation of factors of non-specific resistance of the oral cavity with ozone therapy is manifested by increase in the phagocytic activity of neutrophilic leukocytes, an increase in the activity of lysozyme, and concentration of slgA;

The urgency and relevance of the theme of dissertation. According to the World Health Organization, inflammatory diseases of the eye affects about 16 million of population, accounting for 40.2% of outpatient and up to 50% of the inpatient cases. As for nosological entities, predominance of conjunctivitis (60%) and keratitis (10%) is evident. Those diseases by a decrease in visual functions and lead to serious complications in 26% of cases, and in 19% of cases might even lead to the vision loss are accompanied. The issue of treatment for inflammatory eye diseases until now remains relevant in a medico-social respect worldwide, but fight with corneal blindness is one of the priorities of modem ophthalmology. Search for brand new high-tech treatment methods in ophthalmology is based on unsatisfactory treatment results of existing methods; increased morbidity with specific proportion of patients with severe ophthalmologic pathologies, limiting the use of several treatment methods, and prolonged use of certain drug groups. One of the high technology methods is photodynamic therapy (PDT).
The aim of research work is to improve the treatment outcomes of inflammatory diseases of eye surface (IDES), through the development of safe doses and photodynamic therapy (PDT) power on domestic equipment in experimental and clinical conditions.

The urgency and relevance of the theme of dissertation. Hyperglycemia through several mechanisms is the subject to be to thicken of the basement membrane, and loss of pericytes and capillary’s constriction. Hypocscmiratcd retina releases various factors of angiogenesis, which promotes the formation of new blood vessels, germinating to back hyaloid membrane. These newly formed vessels arc the reason of intravitreal hemorrhaging, in the stage of which arc to be formed fibrovascular bands that lead to traction detached retina, breaking and combined retinal detachment. These situations arc an indication for vitrcoretinal surgery.
Nowadays, only 3 methods shown to be effective in patients with PDR (proliferative diabetic retinopathy): laser image coagulation of retina, surgical treatment -Vitrcoretinal surgery and pharmacotherapy inhibitors of vascular growth factor (Makugcn, proved the effectiveness in clinically significant edema of macular), and antibodies to it (Bevacizumab, research in proliferative diabetic retinopathy (PDR) to be continued).
The aim of research work is to improve is clinic - functional estimation of the efficiency of the previous laser coagulation of retina on the structural and functional outcomes of vitrcoretinal surgery in eyes with proliferative diabetic retinopathy.
The scientific novelty of the research work is as follows:
For the first time in the present study evaluated the outcomes of vitrcoretinal surgery and pre-opcrative structure and function of the eyes with diabetic proliferative retinopathy depending on previous laser coagulation retina. Prove conclusively that previously carried out by retinal laser coagulation contributes to maintaining a higher visual acuity at the time of vitrcoretinal intervention and avoids the development of the most forecasting unfavorable complications of PDR (combined retinal detachment, vapid macular detachment and pre-macular fibrosis, non-absorbablc intravitreal hemorrhage). A more stable condition of the eye at the time of vitrcoretinal surgery can reduce the surgery and avoid tamponade of cavity of the vitreous body with silicone oil.
It is shown that the preservation of a higher visual function after vitrcoretinal interventions contribute to a high prcopcrative visual acuity, prc-retinal laser coagulation, absence tamponadcin cavity ofthc silicone oil with the vitreous body. Factors contributing to the preservation of normal intraocular pressure after vitrcoretinal surgery arc (independently) the lack of tamponadcof cavity of the vitreous body with silicone oilinand retinal laser coagulation previously held.
The study shows that the background or a combination of cataract surgery by phacoemulsification of cataract (FAC) + intraocular lens (IOL) method docs not affect to the structural and functional outcomes of vitrcoretinal surgery in eyes with proliferative diabetic retinopathy.

The aim of the research work is to improve the didactic basis of the intellectual and cultural development of students of medical higher educational institutions in the teaching of the Latin language.
The scientific novelty of the research work are:
the parameters and indicators of intellectual and cultural development were revealed on the part of the methodological support concentrating in the teaching of the Latin language, the evaluation criteria were determined, the systematization of functional factors was improved;
didactic system for designing linguocultural materials was developed on the basis of the assimilation of the lexical, terminological and aphoristic levels of the Latin language;
the contextual-conceptual technology of intellectual and cultural development of students is revealed in teaching Latin language on the basis of logical, abstract and creative thinking and pragmatic components;
the system of teaching archaisms, neologisms and latinisms on the basis of the linguistic and cultural paradigm on hermeneutic and vitogenic technologies of cognitive linguistics was improved.

The aim of the research work. To study linguocultural peculiarities of language units expressing incentive in French, Uzbek and Russian as well as to ground similar and distinctive features of the each.
The scientific novelty of the research work consists of the following:
exaggeration of incentive category in French and Russian sharp and obligatory of the verb moods by the help of the infinitive reflecting values like consideration, respect, politeness in Uzbek and making inccntivcmildcr were determined;
linguocultural peculiarities of language units expressing incentive in the first place arc defined by the types of incentive and status of the communicants in communication situation were proved;
similarities and peculiarities of using prospective, requestive, suggestive in comparative languages in the form of order of the verbs, by the special words which have incentive semas, and in expressing incentives by the help of nouns, adverbs and incentive words as well as their close relation to cultural and mental peculiarities arc given in the examples of literary texts;
speech etiquette and the semas of politeness reflecting behaviour and their speech etiquette units as a process of incentive in French, Uzbek and Russian was explained as a main factor.

The purpose of the research is to develop proposals and recommendations to improve the costs of transportation, based on the specific technological features of autotransport services.
The scientific novelty of the research is as follows:
Proposals were made on the methodology for calculating the prime cost of the services rendered by the enterprises of road transport and the cost of the cost of the services rendered on the basis of deduction of production costs from production costs;
Recommendations have been developed on the efficient use of fuel, storage and production of fuel, including the methods of correct calculation and accounting of deficits on fuel, including fuel and fuel, for car owners;
In order to reduce the costs of the service and correctly organize the account, the procedure for deductions of automobile tires and accumulators has been developed and recommended for practical use;
The company has developed a guideline on the methods of grouping and depreciation of fixed assets in motor transport companies, including the calculation of amortization method for production of passenger and freight cars;
In the automobile transport enterprises, there arc recommendations on depreciation rates, based on the fact that the cost of depreciation of the moving component is practically unmatched, and that some of the cars have problems due to the fact that Article 144 of the Tax Code does not specify the depreciation rate.
The procedure for determining the prime cost for the grouping of the services for road transport services by the items of calculations is recommended.
Implementation of the research results. On the basis of scientific recommendations and practical recommendations on the results of the dissertation on the topic: "Improvement of cost accounting in automobile transport enterprises":
According to the Decree of the President of the Republic of Uzbekistan dated July 12, 2017 and by the July 13, 2017 Act No. 3/2594, the Uzbek Agency for Automobile and River Transport has accepted the following:
the use of fuel efficient fuel, fuel and oil refining and accounting for motor vehicles, storage and storage of motor vehicles, and the correct calculation and accountability of fuel consumption incurred by the driver were eliminated and the confusion of accountability in the enterprise enterprises was eliminated 5.3 percent economic efficiency was achieved.
Improving the utilization of network utility vehicles, discharging and disassembling the battery. As a result of the implementation of this proposal, the cost reduction of services was 2.6%.
At the enterprises of the road transport company. This resulted in an increase in engine oil costs by 4.2 percent due to the reduction in the cost of services and the increase in operating revenue.
At the enterprises of auto transport, the method of calculation of amortization, the rate of depreciation is fixed on the basic means. This proposal was adopted to improve the regulatory and legal documents.
The Ministry of Finance of the Republic of Uzbekistan (in accordance with the Decree № 38 of September 11, 2017 and the reference on September 12, 2012, No. 17-02-35 / 493) has been adopted as follows:
Recommendations for grouping and calculating production costs based on the calculation of production costs for motor transport services;
Recommendations for the improvement of fuel accounting in motor transport enterprises that provide freight and passenger transportation services arc for practical use.

The am of the rsearch work is to develop and improve methods of control in the main cestodoses of animals in Uzbekistan based on the study of epizootology, early diagnosis, and the implementation of a set of health and immunoprophylactic measures.
Scientific novelty of the research is as follows:
for the first time in Uzbekistan, the epizootological features of the main cestodias of sheep and dogs are substantiated, as in the natural conditions in the provision and spread of invasion, the dog-sheep-dog system has a great epizootological and epidemiological significance;
A distribution, seasonal and age-related dynamics, as well as dynamics associated with functional tasks, sex, basic cestodias in definitive and intermediate hosts are established;
the biology of Echinococcus granulosus is substantiated on the basis of the study of its development in the organism of dogs and the factors acting on it; Morphological, clinical, pathoanatomical, helminthoscopic, hematological and biochemical criteria for the diagnosis of sheep echinococcosis have been developed and improved;
a set of special health measures for the main cestodiasis of sheep and dogs was developed;
the effect of modem anthelmintics (hydrogen bromide arecoline, febendazole, fenasal, bithionol, febantel, mebendazole, disillan in the form of solutions of different concentrations, as well as cestane, Brovanol-D, Brovanol-M, Brovanol plus) has been scientifically substantiated in echinococcosis of dogs;
the method of immunoprophylaxis for echinococcosis of sheep has been improved.