No. 1 (2018)

The aim of the research is to study the features of Mycoplasma pneumonia associated with herpesvirus infection in young children for the optimization of the treatment.
Scientific novelty of the research consists of the following:
For the first time, data have been obtained on the frequency of Mycoplasma pneumonia associated with cytomegalovirus and herpes simplex virus type I in young children with community-acquired pneumonia, and their clinical and laboratory features have been revealed;
The parameters of nitric oxide, prooxidant and antioxidant systems in patients with Mycoplasma pneumonia associated with herpesvirus infection has been determined;
The features of cytokine and interferon status of patients with Mycoplasma pneumonia associated with herpesvirus infection have been revealed and their interrelation has been determined;
For the first time, pathogenetically substantiated optimal therapy regimens have been developed for patients with Mycoplasma pneumonia associated with herpesvirus infection, and their effectiveness have been improved.

The aim of the research work is the development of the technology for the complex processing of the brine of the Karaumbet and Barsakelmes lakes, the dry mixed salts of Karaumbet for hydroxide and magnesium oxide, the Tumryuk deposit for sulphate of the highest grade, the utilization of the distillation liquid -waste from soda production.
The scientific novelty of dissertational research consists in the following:
for the first time, method for complex processing of dry mixed salts of Karaumbet for hydroxide, magnesium oxide and sodium sulfate with simultaneous utilization of the waste of the distillery soda plant was developed;
method has been developed for the complex processing of the brine of Karaumbet and Barsakelmes lakes, dry mixed salts of Karaumbet for hydroxide and magnesium oxide, the Tumryuk deposit for sodium sulphate, the purification of the distillation liquid to produce brine suitable for the production of soda ash;
Sodium sulfate of the highest grade from the Tumryuk deposit is produced with high yield of the finished product;
developed technologies for processing the lag of the lakes Karaumbet and Barsakelmes and dry mixed salts of Karaumbet for hydroxide, magnesium oxide, mirabilyte of the Tumryuk field and mirabilyte, isolated from dry mixed salts, for high purity sodium sulphate, purification of the distillation liquid to obtain sodium chloride brine.

The aim of the research. Improvement of the results of surgical treatment of injured children with closed abdominal trauma by standardizing surgical tactics, developing and clinical implementation of unified diagnostic and therapeutic algorithms.
Scientific novelty of the research work: stage therapeutic diagnostic strategy and recommendatory protocols for the management of children with closed abdominal injuries for the provision of qualified emergency medical care;
Identified criteria for an objective assessment of the severity of damage to the parenchymatous organs of the abdominal cavity in children with closed trauma of the abdomen, on the basis of which an integrated program was developed to optimize the choice of tactics for surgical treatment;
the expediency of active surgical tactics and the effectiveness of the use of modem minimally invasive cndovisual technologies in isolated or combined traumatic injuries of the abdominal cavity arc substantiated; Developed and implemented a strategy of treatment of children with closed abdominal trauma ensure the adequacy and effectiveness of ongoing treatment and diagnostic measures that can achieve commonality emergency medical system (emergency medical service) in the Republic of Uzbekistan
For the first time on the basis of experimental and morphological studies proved the effectiveness of new domestic hemostatic collagen film "Glilagin" to stop the bleeding in parenchymal isolated lesions of the liver and spleen.
A optimal diagnostic and treatment algorithm, which allows to determine the indications for various types of treatment, depending on the nature and timing of complications.

The aim of the research work is to explore the traditions and innovations in children upbringing of Uzbeks (the second half of the XX - the beginning of the XX centuries) in ethnological aspect.
The subject of the research is to delve the features of children upbringing in Uzbek families, mutual association of family and social upbringing and cthno-local attributes by historical, ethnographic and cthno-social information.

The aim of research is to study the history of relations between the Republic of Uzbekistan and the United Nations (UN) in 1991-2017.
The scientific novelty of the research work is follows:
There has been illustrated the dynamics of political, social, commercial and economic relations of the Republic of Uzbekistan with international organizations;
There has been shown the problems of reforming of the UN and Uzbekistan’s suggestions to developing the organization, such as increasing the number of permanent members of Security Council of the UN and giving more power to General Secretary of the UN;
The positive aspects of the transformation of the relations between Uzbekistan and the UN justified the deficiencies in the implemented joint programs and projects and suggested ways of their solution;
There have been disclosed problems of the Central Asian region and priorities of cooperation between Uzbekistan and the UN, as well as, the issues to provide sustainable development and peace in the region.
There has been substantiated the relations of Uzbekistan with the UN and its specialised institutions, particularly, in the field of science, education, culture and tourism.

The aim of the research work: is the study of the regularities of the change in the sorption properties of loess rocks with the addition of organomincral additives.
Scientific novelty of research is the following:
the method of changing the sorption properties of loess rocks was first developed by introducing an organomincral complex;
an increase in the sorption properties of loess rocks with the addition of an organomincral complex;
it is determined that the introduction of an organomincral complex into the soil leads to an increase in the content of humus, total and ammonia nitrogen;
a decrease in the transfer of mobile compounds of nitrogen, phosphorus and potassium from the aeration zone to groundwater after introduction of an organomincral complex, which reduces their contamination, is determined.

The aim of the research work is geological-petrographic, petrochemical and geochemical study of plutonic dyke formations of the Kyzylalmasai ore field in the South-Western spurs of the Chatkal ridge.
Scientific novelty of the research:
the association of lamprophyres (camptonites, odidites, kersantites) was first established within the gold-silver deposits of the Kyzylalmasai ore field;
for the first time geological-petrographic, petrochemical and geochemical features of plutonic dike formations of the Kyzylalmasai ore field were identified;
petrological-geochemical criteria of ore-bearing of lamprophyre magmatism of the Kyzylalmasai ore field have been developed;
plutonic dikes are defined as indicators of the deep forecast of gold-silver mineralization.

The aim of the research is to optimize early diagnosis and develop approaches to pharmacotherapy taking into account the indices of the functional state of the kidneys and ncurohumoral systems in patients with chronic heart failure (CHF) and to develop optimal pharmacotherapy regimens.
The scientific novelty of the research is as follows:
for the first time early markers of kidney dysfunction (K.D) in patients with CHF and deterioration of renal blood flow were justified, as prognostic predictors of the lesion of the tubulocpithclial apparatus of the kidneys;
the dependence of the clinical course, the level of ncurohumoral factors (HA, MNUP and Al) and parameters of left ventricular remodeling (LVR) on the degree of K.D parameters (glomerular filtration rate (GFR) and fermenturiya) in patients with CHF was proved;
for the first time, the correlation between the indices of the functional state of the kidneys and the hemodynamic parameters of the carotid and renal arteries was proved in patients with CHF;
the comparative efficacy of lisinopril and losartan in patients with I-III FC of CHF on ncurohumoral factors and functional state of the kidneys, renal blood flow parameters and cardiovascular remodeling processes was first evaluated;
optimized approaches to the pharmacotherapy of CHF therapy, taking into account disturbances in kidney function and ncurohumoral factors.

The aim of research work elaboration of methods of ampcromctrical titration of ions Hg2+, Ag' and Pd2, by solutions of thionalid and thiourea in water solutions and extracts with improvement metrological characteristics (selectivity, rightness and some others) and analytical parameters.
The scientific novelty is as follows:
dependence of analytical signal (AS) on nature and concentration of outside interfering cations and anions:
pH of medium, phone electrolytes and buffer mixtures has been determined;
influence of tension give on indicating electrodes has been investigated;
spccifical reagent at determination of ions Hg2+, Ag' and Pd2 have been determination, electrochemical behavior of used reagents and complex compounds;
has been investigated and on the base of obtained results conditions of ampcromctrical titration of above-mentioned ions by solutions of thionalid and thiourea have been optimized of their determination individual solutions: binary, ternary and more complex mixtures what has allowed in to simplisite and accelerate of analysis of some real natural objects and in dust real materials with improvement metrological characteristics and analytical parameters.

The aim of research work is determination of chemical and chemical properties of saline soils and mobile sludge with the help of multifunctional structures on bases of water-soluble SAS (surface-active substance) and industrial waste
The scientific novelty of the research work is the following:
the colloid-chemical principles of the selection of reagent compositions for the chemical fixation of mobile saline soils and sands arc determined;
the mechanisms of the fixing effect of the developed multicomponent mcliorants from chemical reagents and industrial wastes arc grounded;
optimal conditions for fixing saline sands of water-soluble polymers have been established, which is connected with the transition of the polymer from the soluble form to the insoluble form due to its transformation from two-dimensional structure to three;
optimum conditions for phytomclioration arc revealed: the mechanical strength of the crust is 2.6-3.0 MPa and the number of waterproof aggregates is 70-80% on the basis of the proposed methods for fixing mobile saline sands;
the mechanism of structure formation under the action of complex additions of Са(ОН)г + SDB and Са(ОН)г + EG in systems “soil-salt-structurant” is defined, which reduces to the interaction of the additive with water-soluble layers with the formation of gel-like products adhesively fixed on clay particles, and the adsorption and adhesion of tumors is provided by the surface active component;
the optimal conditions for the “soft” fixation of mobile saline soils and sands with additives of sawdust and leaf fall, which increase the porosity and moisture capacity of the surface crust ensuring the development of plants.

The urgency and relevance of the dissertation topic. Many scientific and applied studies (conducted at the world level), in many cases, arc reduced to the study of ill-posed boundary-value problems for partial differential equations. The basis of the theory of ill-posed problems laid in the middle of the last century and they arc associated with problems of great practical importance. The main object of applied investigations on conditional correctness and creation of solution of boundary-value problems of elliptical equations becomes very important in hydrodynamics, geophysics and electrodynamics. A study of ill-posed problems for linear elliptical system of the first order in space domains is applicably important.
The aim of the research work is to get the regularization in the bounded and unbounded domain, criteria for the decidability solution of the Cauchy problem for the linear elliptic system of the first order.
Scientific novelty of the research work is as follows:
- the Cauchy integral formula is created, for generalized holomorphic and generalized potential vector, generalized system Cauchy-Riemann equations with quaternion parameter and integral formula of Stratton-Chu for a homogeneous system of Maxwell equations in the unbounded domain with non-compact boundary arc obtained;
- for the generalized Cauchy- Riemann equation systems in the bounded and unbounded domain and regularization of the solution of the Cauchy problem arc solved and the criteria of decidability is found;
- for the generalized system of Moiseil-Thcodoresco equations an analogue of Carlcman formula is obtained and criterion for the solvability of the Cauchy problem is proved;
- the Cauchy problem for generalized Cauchy-Riemann equations in multidimensional bounded and unbounded domains arc solved an analogue of Carlcman formula is detained. Using this formula the regularization of the Cauchy problem is constructed and the solvability criterion is found;
- Carlcman formula and regularization of the Cauchy problem for the homogeneous system of Maxwell's equations are constructed. An analogue of Fock-Kuni theorem for a homogeneous system of Maxwell's equations is proved;
- the regularization solution of Cauchy problem for generalized Cauchy-Riemann equations and homogeneous system of the time-harmonic Maxwell and Dirac equations with a complex quaternion parameter arc obtained .

The aim of the research is to provide scientific suggestion and to develop practical advice on perspectives of increasing living standard degree based on development of service sphere.
Scientific novelty of the research consists of the following propositions:
new definition of «living standards of people» is given which comprises the enhanced form of services;
“Enrichment of labour market” and “Satisfaction degree of work power requirement in labour market” are given as target for evaluating the enhancement of labour market which form income in service sphere;
in order increase the efficiency of social service mechanism forwarded toward low income families suggestions have been developed highlighting possibilities to cam additional income with the help of correct distribution of state budget;
it is proved that provision of service in the field of service helps to improve living standards of people in the future and its scientific foundation has been identified in development of service sector forecast for 2018-2021 years.

The aim of research work is the isolation of the alkaloids of the N. schoberi L. plant, the determination of the structure of new alkaloids, the performance of chemical correlations and synthesis reactions.
Scientific novelty of the research work:
It is isolated from the plant N.schoberi L. 22 alkaloids in an individual form;
It is isolated from the plant N.schoberi L. 4 new alkaloids (comavine, acetylcomavine, N-methylnitrarine and N-allylisonitrarine), their structure was established;
It is determined that 18 alkaloids isolated from N.schoberi L. (10 of the isolated substances belong to the indole, 3 - to spiropiperidine, 2 - to quinolizidine and 3 - to quinazoline alkaloids;
It is synthesized alkaloids comavine, acethylcomavine, N-methylnitrarine and N-allylisonitrarine.

The aim of the research work is to create scientifically proved proposals and recommendations through an analysis of the main directions of the development of secondary schools in Karakalpakstan during the years of independence.
Scientific novelty of the research work is as follows:
the prognostic indicators (quantitative and qualitative indicators, dynamic characteristics, synergetic, hermeneutic, anthropological and phenomenological principles) of the development of the educational system of schools in Karakalpakstan improved by the synergistic, hermeneutic, anthropological and phenomenological principles in the perspective;
the qualimctric steps and a component of the effectiveness of the technology monitoring of the quality education in secondary schools is improved on the basis of the self-evaluation and self-development criteria;
the content of the education of a future model for the creation of educational -methodological support in the secondary education schools, the components of the management organization and the education quality arc improved by providing a continuous methodological service of innovation activity, technology for the development of the social intelligence of students;
the increase in the effectiveness of spiritually enlightening work in secondary schools is improved on the basis of the effectiveness of educational technology of personality formation with high spirituality, the intensity of feedback, the integration of criteria for the interactivity of the pedagogical control.

The aim of the research work is to define the methodological basis of the organization of education of mathematical analysis in the higher education institutions, as well as to define the method of its practical use.
The scientific novelty of the research work is as follows:
Didactic opportunities for systematic approach to modular teaching is improved based on identification the content of inventive, modeling and experimental components;
Methodological opportunities of teaching mathematical analysis improved based on systematization of functional factors (pedagogical, psychological, conceptual, technological, innovative) of modular teaching;
The content is defined the assessment-control components, methodology of practical trainings projects on the basis of client requirements;
The teaching process of mathematical analysis in higher education institutions is improved based on designing modules using modular technology.

The aim of the research work: improvement of methods of development the speed-strength and technical-tactical training of women footballers of high qualification
in a year’s cycle.
Scientific novelty of the study:
appropriateness of the dynamics of speed-strength training of high-qualified women footballers in various stages of a year’s cycle has been revealed;
most typical quantitative features of technical-tactical actions of women footballers in the gaming process have been identified;
interrelation between indexes of technical-tactical actions of women footballer and the level of their speed-strength training has been revealed;
worked out methodology of improving the speed-strength qualities of high-qualified women footballers have been implemented into practice.

Диссертация мавзусининг долзарблиги ва зарурати. Жаҳон иқтисо-диётига интеграциялашув жараёнлари жадал ривожланиб бораётган бир вақтда қишлоқ хўжалигининг барқарор ривожланиши муҳим омиллардан бирига айланиб бормокда. Ушбу йўналишда бугунги кунда аграр сектор салоҳиятининг салмоқли қисмини ташкил этувчи сабзавотчилик маҳсулотларини етиштириш ва сифат даражасини ошириш муҳим аҳамият касб этмокда. Зеро, Халқаро диетологларнинг тавсиясига кўра, инсон истеъмол қиладиган озик-овкатнинг камида 50 фоизини мева ва сабзавотлар ташкил этиши зарур1.
Мамлакатимиз табиий-иклим шароити сабзавотчиликни ривожланти-ришда кулай ҳисобланиб, тармоқ рақобатбардошлигини ошириш сабзавотчилик мақсулотларига бўлган ички бозор талабини тўлиқ таъминлаш, экспорт салоҳиятини ошириш эвазига юқори даромадли тармоқка айлан-тириш, шунингдек, кўшимча ишчи ўринларини яратиш, энг асосийси аҳо-лини тиббий меъёрларга мос равишда сифатли маҳсулотлар билан узлуксиз таъминлаш каби ижтимоий масалаларни ҳал этиш имкониятини беради. Аммо, кейинги йилларда тармок имкониятларидан етарлича фойдаланмаслик улар фаолияти самарадорлигининг ошишига салбий таъсир кўрсатмокда. Шу боис, Президентимиз томонидан қишлоқ хўжалигида “...таркибий ўзгартиришларни чукурлаштириш ва қишлок хўжалиги ишлаб чиқаришини изчил ривожлантириш, мамлакат озиқ-овқат хавфсизлигини янада мустах-камлаш, экологик тоза маҳсулотлар ишлаб чиқаришни кенгайтириш, аграр секторнинг экспорт салоҳиятини сезиларли даражада ошириш”2 масалалари стратегик вазифа сифатида белгилаб берилди.
Дунёдаги глобал иқлим ўзгариши, ижтимоий-демографик ҳолат ва унга мос равишда озик-овкат махсулотларига талаб ошиб бориши натижасида “бугунги кунда ривожланаётган мамлакатларда бир киши учуй тавсия этилган кундалик 400 грамм ўрнига жуда кам микдорда - бор-йўғи 150-200 грамм мева ва сабзавот истеъмол қилинмокда”3. Шу нуктаи назардан бугунги кунда республикамизда сабзавотчилик тармогини ривожлантириш, хусусан, ҳимояланган ер сабзавотчилигида махсулот етиштиришнинг ташкилий-иқтисодий механизмларини такомиллаштириш оркали сабзавот махсулот-ларини етиштиришнинг узвийлиги ва нарх барқарорлигини таъминлаш каби масалаларни хал этиш бўйича илмий тадкикот ишларини амалга ошириш долзарблик касб этмоқда.
Ўзбекистон Республикасининг «Фермер хўжалиги тўғрисида»ги, «Деҳқон хўжалиги тўғрисида»ги (1998) қонунлари, Ўзбекистон Республикаси Президентининг 2017 йил 21 июндаги ПҚ-3077-сон “Махаллий экспорт килувчи ташкилотларни янада қўллаб-кувватлаш ва ташки иқтисодий фаолиятни такомиллаштириш чора-тадбирлари тўғрисида”ги Қарори ва Ўзбекистон Республикаси Президентининг 2017 йил 7 февралдаги ПФ-4947-сон «Ўзбекистон Республикасини янада ривожлантириш бўйича Ҳаракатлар стратегияси» Фармони ҳамда мазкур фаолиятга тегишли бошқа меъёрий-ҳуқуқий ҳужжатларда белгиланган вазифаларни амалга оширишга ушбу диссертация тадқиқоти муайян даражада хизмат қилади.
Тадқиқотнинг мақсади қишлоқ хўжалигини модернизациялаш шароитида ҳимояланган ер сабзавотчилигини ривожлантиришнинг икти-содий асосларини такомиллаштириш бўйича илмий асосланган таклиф ва амалий тавсиялар ишлаб чикишдан иборат.
Тадқиқотнинг илмин янгилиги куйидагилардан иборат:
фермер ва деҳқон хўжаликларида иссикхоналарда интенсив ва ресурс-тежамкор технологиялардан фойдаланишни кўзда тутувчи сабзавот экин-ларини парваришлаш ва маҳсулот етиштириш бўйича намунавий технологик карта ишлаб чиқилган;
ривожланган давлатлар тажрибаларини ўрганиш асосида республика худудларининг ижтимоий-иктисодий ривожланиши, бозор талабини ҳисобга олган ҳолда иссикхоналарда сабзавот маҳсулотлари етиштиришнинг замонавий усулларини жорий қилиш бўйича таклифлар ишлаб чиқилган;
иссикхоналарда махсулот етиштирувчи субъектлар фаолиятини муво-фиқлаштирувчи уюшмаларни ташкил этиш, уларнинг ташкилий-бошқарув тузилмаларини шакллантириш бўйича таклифлар ишлаб чикилган;
иссикхоналарда сабзавот етиштирувчи тадбиркорлик субъектлари учун бошлангич сармояларни шакллантириш жараёнини кредитлаш ва сугурта-лашнинг рагбатлантирувчи тизимини жорий килиш юзасидан тавсиялар ишлаб чикилган.
Хулосалар
1. Сабзавот маҳсулотларини очиқ ва ҳимояланган майдонларда етиш-тириш усулларини бевосита алоқадорликда ривожлантириш тармокда ишчи кучига бўлган талаб ва ишлаб чикариш жараёни узвийлигини таъминлаган ҳолда йил давомида аҳолининг сабзавот маҳсулотларига бўлган эҳтиёжини кондириш имконини беради. Шу сабабли, тадқиқотлар натижасида ҳимоя-ланган ер сабзавотчилигининг ўзига хос хусусиятлари тадкиқ этилган бўлиб, унинг ишлаб чиқариш ва иқтисодий самарадорлигини оширишда мазкур ху-сусиятларни ҳисобга олиш муҳим саналади
2. Тадқиқотлар натижасида иссикхонада сабзавот етиштиришнинг самарадорлигини ифодаловчи кўрсаткичлар аниклаштирилди ва тизимлашти-рилди. Ушбу кўрсаткичлар тизими тегишли умумиқтисодий индикаторларни камраб олган ҳолда, соҳада барча турдаги ресурслардан фойдаланиш самарадорлигини баҳолаш имконини беради.
3. Иссикхона сабзавотчилигини ривожлантиришда хориж тажрибасини ўрганиш натижаларини умумлаштириш натижасида, уларнинг республика-мизда қўллаш зарур бўлган қуйидаги жиҳатларини таклиф этамиз. Хусусан:
замонавий енгил конструкцияли, энергия тежовчи ва мукобил энергия манбалари асосида ишлашга мўлжаллаб куриладиган иссиқхоналар майдон-ларини кенгайтириш;
етиштириладиган сабзавотлар уруғчилигини ривожлантириш ва уруғ билан таъминлашнинг самарали усулларини жорий этиш, иссиқхона маҳсу-лотлари етиштирувчи барча турдаги хўжалик субъектларига ресурс таъми-ноти тизимини ривожлантириш шароитларини яратиш;
иссикхона сабзавотчилиги билан шуғулланувчилар ўртасида ўзаро кооперацией алокаларни ривожлантириш, кооперативлар ва уюшмалар томо-нидан товар ишлаб чикарувчиларнинг манфаатларини химоя килиш тизимини жорий этиш; маҳсулот етиштирувчиларга молиявий имтиёзлар бериш, иссиқхона сабзавотчилиги соҳасини кадрлар билан таъминлаш, хўжалик субъектлари ходимларининг малакасини ошириш бўйича курслар ташкил этиш ва хорижий давлатларга тажриба алмашиш тизимини жорий этиш.
4. Хўжалик юритиш шаклларининг иссиқхона турларидан фойдала-нишни қиёсий баҳолаш аксарият деҳқон хўжаликлари ва аҳоли томорқа-ларида кам сарф-харажат талаб этадиган, айниқса, маҳаллий типдаги кичик хажмли иссиқхоналардан фойдаланиб, сабзавотчилик маҳсулотлари етишти-рилаётганлигини кўрсатади. Фермер хўжаликлари ва хусусий тадбиркор-ларнинг аксарияти эса кўпрок замонавий технологияларга асосланган катта ҳажмдаги ер майдонларида куриладиган иссикхоналарда сабзавот махсу-лотлари етиштирмокдалар.
Тахдилларга кўра, иссикхоналарда сабзавот маҳсулотлари етиштириш имкониятларидан тўларок фойдаланиш максадида уларни ҳудудий жойлаш-тириш талаб этилади. Мисол учун, анъанавий иссикхоналарга нисбатан замонавий (автоматлаштирилган, гидропоника усулидаги) иссиқхоналардан фойдаланиш натижасида 1 м2 майдонда сабзавот маҳсулотларининг ўртача хосилдорлигини 15-20 кг га, даромад микдорининг эса 75-100 минг сўмга ортишини таъминлаш асослаб берилган.
5. Иссиқхона сабзавотчилигининг амалдаги намунавий технологик карталарга асосан бир гектар очиқ ва ёпиқ майдонларда сабзавот махсу-лотлари (бодринг) етиштиришнинг асосий ишлаб чиқариш ва иқтисодий кўрсаткичлари таққослама таҳлилига кўра иссиқхоналардаги бодринг хосил-дорлиги очиқ майдонларга нисбатан 170 центнерга ортиқ, рентабеллик даражаси эса мос равишда 2 баравардан кўпроқни ташкил этади.
Тахдилларга кўра, бир хил типдаги бир минтақада жойлашган иссикхоналарда сабзавот етиштириш учун сарфланган ресурслар микдорида кескин фаркланишлар мавжудлиги махсулот етиштирувчиларнинг аник илмий асосланган меъёрлар асосида фаолият юритмаганлигида намоён бўлди. Шу муносабат билан муаллиф томонидан ёпик усулда сабзавот етиштиришнинг намунавий технологик харитаси ишлаб чикилиб амалиётга жорий этилди.
6. Бугунги бозор муносабатлари шароити ва конуниятлари иссикхона сабзавотчилигида инновациялардан кенг фойдаланиш заруриятини талаб этмокда. Иссикхона сабзавот махсулотлари ишлаб чикариш хажмини кўпай-тириш, уларнинг хосилдорлигини ошириш, мехнат харажатларини камай-тириш ва махсулот сифатини ошириш илғор энергия тежовчи янги техно-логияларни жорий этилишига ва замонавий илмий-техника базасининг яратилишига богликдир.
Республикамиз шароитида кишки ва бахорги иссикхоналарда махсулот ишлаб чиқарилиши боисдан, ушбу даврда энергия ресурсларига (табиий газ, иссиклик энергияси, электр энергияси ва бошқалар) бўлган талаб кескин ортади ва янги ҳосилга замин (уруғ экиш, кўчат материалларини экиш, ҳосилни шакллантириш ва бошқалар) яратилади. Тахлилларга кўра, иситиш харажатлари жами харажатларнинг қарийб 40 фоизидан ортигини ташкил этмокда. Шу билан бирга иссикхона сабзавотчилиги билан шугулланувчи деҳқон хўжаликларига табиий газдан фойдаланишнинг чеклаб қўйилиши оқибатида етарли микдорда иссикликка эга бўлмасдан экинлар бир кисмининг нобуд бўлишига ва олинадиган хосилнинг камайишига, пировард натижада махсулот ишлаб чикариш самарадорлигининг пасайишига олиб келмокда.
Шу боисдан илмий-техника тараккиёти натижаларига асосланган энергиянинг мукобил манбаларида (биогаз, куёш ва шамол энергияси) ишловчи самарали иссикхоналарни куриш ва улардан фойдаланиш зарурияти юзага чиқмокда. Бундай иссикхоналарда киш ва бахор ойларида етишти-рилган сабзавотлар нархи юкори бўлиши нафакат харажатларни коплаш, балки юкори фойда олиш имконини беради.
7. Тизимда олиб борилган кенг кўламли ислоҳотлар натижасида сабзавот етиштирувчи фермер ва деҳкон хўжаликларида экспорт фаолиятини ривожлантиришни рағбатлантириш, улар томонидан етиштирилаётган сабзавот махсулотлари сифатини ташки бозор ва халкаро стандартларга тўлик жавоб берадиган холда етиштириш имкониятларини яратмокда. Аммо, иссикхона хўжаликлари фаолиятини мувофиклаштиришнинг ягона тизими мавжуд эмаслиги, янги технологиялар асосида замонавий иссиқхоналар куриш ва мавжудларини реконструкция қилишни қўллаб-қувватлаш меха-низмлари жорий этилмаганлиги сабабли экспорт салохиятини янада ошириш ва кишлок ахолиси учун янги иш ўринларини яратиш имкониятларини чекламокда. Шу сабабли “Ҳимояланган ерларда сабзавот махсулотлари етиштирувчилар уюшмаси”ни ташкил этиш мақсадга мувофикдир.
8. Тадқиқотларга кўра, иссикхона сабзавотчилигини ривожлантиришда амалдаги кредитлаш, солик, сугурта каби молиявий институтлар фаолиятини хам такомиллаштиришни талаб этади. Бунда иссикхона сабзавотчилиги субъектлари учун бериладиган кредит фоиз ставкаларини амалдагига нисбатан 50 фоизгача камайтириш, мос равишда олинган кредит маблагларини коплаш муддатларини узайтириш, лизинг шартларини, яъни дастлабки тўлов муддатини 3 йилгача имтиёзли равишда кечиктириш, коплаш муддатини 5 йилга узайтириш, амалдаги иссиқхоналарни мулк сифатида сугурталаш тарифларини 10 фоиздан 6 фоизгача, хосил сугуртаси тарифларини 8 фоиздан 5 фоизгача камайтириш орқали республикада иссикхона сабзавотчилиги тизимининг баркарор ривожланишини таъминлаш асослаб берилган.

The urgency and relevance of the dissertation topic. Viral hepatitis remains as the most important medical and social problem in the world. According to the World Health Organization, 257 million people arc infected with chronic hepatitis В (СНВ). Approximately 686 thousand people die annually from hepatitis В infection, including cirrhosis and liver cancer as a result of chronic hepatitis В infection. In the world, the lethality from the consequences of the progression of the infection associated with the hepatitis В virus ranks 7th in the structure of infectious pathology. The introduction of modem virological methods, the use of non-invasive methods in the diagnosis of the liver fibrosis, the improvement of preventive measures, taking into account genetic polymorphism and the degree of fibrosis, remain as the priority arc as for scientific research.
The aim of the research work: To reveal regularities and prognostic significance of factors of progression of chronic viral hepatitis В and D in cirrhosis of the liver (LC), to study clinical diagnostic and preventive aspects of LC taking into account the true prevalence and economic burden.
The scientific novelty of research is the high frequency of circulation of genotype D on the territory of the republic and found out the value of genotype D in the progression of HBV infection is;
the effectiveness of the use of scrum markers of hepatic fibrosis WFA+-M2BP for the prognosis of viral cirrhosis was first determined;
the influence of HBV viral load and human genetic factors as a prognostic marker of the progression of chronic hepatitis B, D and the formation of LC;
for the first time interleukin 28B was used as a prognostic marker of the transition of chronic hepatitis D to cirrhosis of the liver;
scientifically justified the timely treatment of antiviral drugs of direct action - analogues of nucleotides and nucleosides with the calculation of economic costs for the treatment of chronic hepatitis В and D in comparison with LC.

The aim of the research work is to determine conducting research on the use of medicines and quantitative and qualitative assessment of the rationality of their use in RA patients.
The scientific novelty of the research is as follows:
Clinico-pharmacological audit conducted applied medicines for RA, A, В and C groups of analyzes, the comparative gravity used for the treatment of the disease, a violation of the standard treatment system was proved.
In the framework of the standard treatment of RA with basic drugs, the insufficient use of methotrexate in the basis leads to the existence of the causes of manifestation of comorbid pathology.
The drugs used to treat RA arc not correctly distributed in classes А, В, C. The class includes the most expendable group of drugs (class A), the remaining groups of drugs arc shown to be the least expensive.
It has been established that the use of small quantities in the treatment of RA preparations of the "first" line, application of the treatment system gives rise to an increase in the disability condition.

The urgency and relevance of the topic of the dissertation work. Currently, rheumatoid arthritis (RA) is one of the topical problems of medicine in the world. RA is a multifactorial disease that occurs among people of different ages, proceeds with damage to the internal organs, which leads to a decrease in the operability and early disability of patients. In developed countries, the incidence of RA among the general population is 0,5-2%, and this figure is increasing every year. In women, RA is 2-3 times more common than in men. In patients with rheumatoid arthritis, a decrease in life expectancy compared with the general population by 3-7 years is observed. In the absence of effective therapy, the life expectancy of RA patients is lower by 3 years in women and by 7 years in men. The presence of gastrointestinal pathologies among internal injuries of internal organs in RA ranges from 13% to 60%.

The aim of the research is to base the opportunities of effective usage of Rumi’s spiritual and moral views in educational process and to implement them into practice.
The scientific novelty of the work:
The spiritual heritage of Jaloliddin Rumi has been categorized as anthology writing, interpretation, translation and scientific reascarch. The theoretical opportunities of using them in educational process have been developed from pedagogical aspect;
The principles as analogy, moral influence, spiritual debate have been developed on the basis of using the content of stories, fables, eposes, witty sayings and folklore samples found in “Masnavi Manavi” and prioritizing the upbringing of a person as morally developed;
The pedagogical opportunities of using such notions as “faith”, “tolerance”, “strong will”, “conscience”, “propriety” in the educational process directed at person have been expanded on the basis of optimizing the relations in family, community, teacher and student;
The scientific recommendations have been worked out on developing spiritual and moral thinking on the basis of the content in Jaloliddin Rumi’s spiritual heritage, which aims at forming a person’s spiritual and moral upbringing and develops it.

The aim of research work is to develop scientific proposals and practical recommendations on economic-ecological development of coal-mining branch of fuel and energy complex in the context of modernization.
Scientific novelty' of the research work is as follows:
proposed a step-by-step mechanism for improving the integrated economic and environmental activities of enterprises of the fuel and energy complex;
an integration system for integrating interactions between environmental programming subjects and the environment in the coordination of activities of integrated economic and environmental activities was improved;
a model for interaction of ecological, economic, social factors and maximization of economic-environmental efficiency of the complex usage of coal resources has been elaborated;
the organization-economical criteria for the development of the energy-chemical-resource complex was introduced.

The aim of the research is to improve the professional competence of future English teachers in the process of forming interest in the culture of England.
The scientific novelty of the research is as follows:
motivational, cognitive, technological, social-communicative and reflexive stages of the level of professional competence of future English teachers are defined;
psychological and pedagogical conditions for the development of the level of the motivational sphere, sensory-emotional activity, professional and personal competence of students to the culture of England are characterized;
Methods for the formation of an interest in English culture in future English teachers have been improved on the basis of organizing extracurricular classes on the topics "Culture of England", "Modern Approaches to Culturology", "Competencies of the Modem Teacher";
for the purpose of professional and competent improvement of teachers of the secondary school, the methodical manual "Professional Competences of the Modern Teacher" was developed, as well as recommendations "Teacher's professional competence development" for teachers of the English language were prepared and introduced into the teaching and educational process.

The aim of the research work is the development effective compositions composite wooden-plastic materials based on local raw materials and wastes of productions.
Scientific novelty of the research work:
the possibility of creating import-substituting woody-plastic composite materials based on polymer binders and wooden fillers from the stems of cotton, used in construction, furniture and engineering industry is scientifically substantiated;
the basic regularities of changes of physical and mechanical properties of wooden-plastic composite materials depending on structure, type and content of woody filler, obtaining from the stems of cotton, a polymer binders, which are components of the composite mass, considering as a heterogeneous material is studied;
the possibility of the transmission of the crushed mass of cotton stalks, through the pneumatic separator makes it possible to obtain a multilayer composite wood-plastic material on this basis and the optimum sizes of filler particles are determined, which has fibrous particles in the composition, which do not allow accumulation and clogging of the pneumatic unit;
the requirements for crushed mass, which is the basis for the development of technology for woody fillers from the stalks of cotton and the production of woody-plastic composite materials and products from them are developed;
it is established that the developed woody-plastic composite slab materials have high physical-mechanical properties, in comparison with woody chipping slabs, which are directly produced from the wood.

The purpose of research work is to study the interdependence of the pathogenetic and clinical features of the development of juvenile glaucoma and progressive myopia in their combination, to develop clinical criterias for optimizing the early diagnostics of juvenile glaucoma on the base of progressive myopia and to increase the effectiveness of treatment of concominant pathology.
The scientific novelty of the research work is as follows:
it is established that the presence of dysgenesis angle of the anterior chamber (CCP) leads to a violation of the outflow of the VGL and a gradual increase of the level of intraocular pressure (ЮР), which contributes to the growth of the eyeball with the development of late hydrophthalmic and it is one of the pathogenetic factors of development of myopia;
it was revealed that a high level of hydroxyprolinc in the blood scrum with a combination of progressive myopia and juvenile glaucoma indicates the intensity of collagen destruction in the extracellular matrix (ECM) and leads to its insufficiency. Collagen deficiency, in turn, creates conditions for the sclera to stretch with an increase in ЮР;
scientifically substantiated the technique of a consistent discharge-loading test for the early diagnostics of juvenile glaucoma on the base of progressive myopia;
firstly used drugs that reduce the intensity of collagen destruction in the ECM system in combination with pathology, which contributed to the stabilization of the myopic process;
developed and proposed a scientific concept for the development of the pathological process in juvenile glaucoma on the base of progressive myopia taking into account the mutually aggravating pathogenetic factors of these two diseases.