O Teshaev, A Murodov, R Sadikov, N Malikov
Objective: Improve the treatment of purulent destructive wounds by topical application of CO2 laser and photodynamic therapy in the experiment. Materials and methods: purulent wound model reproduced in 80 male rats by MP Thick (2002) with some modification. Animals from the third day were divided into 4 groups:
1) 20 rats with physiological regeneration, 2) 20 rats with standard therapy, and 3) 20 rats PDT 4) rats 20 inclusion complex treatment with conventional methods, the CO2 laser (JZ- 3A) 3 times daily until the wound cleansing from necrotic raids and PDT. Studied plane geometry, healing time, peripheral blood counts and morphology of biopsies from the wound bed and the wall on the 1st, 3rd, 7th and 10th day of the experiment.
Results. Photodynamic therapy in a CO2 laser complex was not sufficiently effective invasive treatment of purulent wounds and allows to recommend its use in clinical practice for the treatment of local purulent-destructive diseases of soft tissues. Complex application of PDT and CO2 laser leads to an earlier cleansing from the pus, the active formation of granulation tissue and shortening deadlines complete epithelialization of
the wound surface. Conclusions: Complex treatment with CO2 laser and photodynamic therapy is the most effective, as compared to other methods studied separately
