N Shavazi, M Lim
The purpose of the study: examine the effectiveness of using acetylcysteine inhalation in the treatment of acute obstructive bronchitis in infants. The study involved 52 patients with acute obstructive bronchitis. All patients were randomly divided into two groups. 26 patients were observed in group I (control) who re-ceived therapy as mucolytic ambroxol orally. 26 patients included in the II group were treated with inhaled nebulized acetylcysteine through compression nebulizer via 10% solution. According to the study, II group of patients, treated with nebulized acetylcysteine, were noted: significant reduction in the intensity of cough compared with the control group at 5 and 8 days (P<0,05; P<0,01), the improvement of sputum discharge on 5, 8 days (P<0.01; P<0.05), improvement of SSA scale indicators on 3-8 days of the disease (P<0.05; the P<0.001), reduced duration of oxygen therapy and length of hospitalization (P<0,01; P <0,01). Thus, using of acetylcysteine as an nebulized inhalation can be regarded as effective and safe drug for the treatment of children with acute obstructive bronchitis.
