SCIENCE AND INNOVATION IN THE
EDUCATION SYSTEM
International scientific-online conference
112
ASSESSMENT OF THE SEVERITY OF PATIENTS WITH ABDOMINAL
CEPSIS
Sattarov Shokir Khasanovich
1,2
Atoeva Mokhigul Otabekovna
3
Usmonov Amirbek Usmonovich
3
Saymurodova Shaxnoza Ziyodullayevna
3
1
Samarkand branch of the Republican Scientific
Centre for Emergency Medical Care
2
Department of Surgical Diseases and Urology.
Samarkand State Medical University.
3
Bukhara State Medical Institute named after Abu Ali ibn Sino.
https://doi.org/10.5281/zenodo.13828637
Relevance of the research.
Abdominal sepsis in disseminated purulent
peritonitis is a serious condition requiring a comprehensive approach to
diagnosis and treatment. The aetiology includes polymicrobial infections and
intra-abdominal pathologies, whereas the pathogenesis is related to systemic
inflammation and haemodynamic disturbances. The incidence of
disseminated purulent peritonitis (PPP) remains high, especially among
patients with risk factors, emphasising the need for improved preventive and
treatment strategies.
Purpose of the study.
To conduct an objective assessment of the
severity of the condition and prognosis of patients with abdominal sepsis.
Materials and methods of research.
The study is based on the results of
treatment of 276 patients with widespread purulent peritonitis admitted to the
surgical department of the Samarkand branch of RCEMP in the period from
2015 to 2024. Patients were conditionally divided into two groups: 132 (47.8%)
patients were operated on in 2015-2019, who were included in the comparison
group, and 144 (52.2%) patients were operated on from 2020 to 2024, who
were included in the main group.
Results of the research.
Before surgery, the severity of the patients'
condition was determined according to the APACHE II scale, SOFA, Mannheim
peritonitis index (MPI) and severity of abdominal sepsis. For detailed
characterisation of quantitative indices we distributed the patients in the
studied groups according to the manifestations of abdominal sepsis by the
degree of systemic inflammatory response syndrome (SIRS). The combined
surgical and endoscopic method of treatment was mainly used in patients with
stable parameters of homeostasis, average degree of intoxication. According to
the severity of septic reaction, patients with widespread purulent peritonitis
SCIENCE AND INNOVATION IN THE
EDUCATION SYSTEM
International scientific-online conference
113
were divided into 4 groups. The distribution of patients by severity of abdominal
sepsis is presented in Table 3. Abdominal sepsis was absent in only 33 (11.9%)
patients. Abdominal sepsis without organ dysfunction was found in 127
(46.0%), with monorgan dysfunction - in 74 (26.8%), with multiorgan
dysfunction - in 42 (15.2%) patients. In 117 (42.4%) patients with widespread
purulent peritonitis were found to have concomitant diseases from different
organism systems, which significantly aggravated the course of the disease
(Table 4).
Conclusions.
Thus, each of the prognostic scales has its advantages and
limitations. APACHE II and SAPS II are highly accurate but difficult to calculate.
SOFA is useful for monitoring the patient's condition over time but may be less
accurate in predicting outcomes in the absence of organ failure. IPI is easy to use
and specific for peritonitis but has limited accuracy in severe comorbidities.
References:
1.
Асраров А. А., Абдуллаев У. Б., Тагаев К. Р. Эффективность
программированных
релапаротомий
в
лечении
острого
распространенного гнойного перитонита //Врач-аспирант. – 2010. – Т. 43.
– №. 6.1. – С. 115-122.
2.
Рузибоев С. А., Саттаров Ш. Х. Результаты лечения острого разлитого
гнойного перитонита с применением лапаростомии //ББК 1 А28. – 2020. –
С. 21.
3.
Саттаров Ш. Х., Рузибаев С. А. Пути коррекции эндотоксикоза при
остром перитоните (обзор литературы) //Достижения науки и
образования. – 2022. – №. 1 (81). – С. 82-87.
4.
Саттаров Ш. Х., Рузибаев С. А., Хурсанов Ё. Э. Оптимизация пути
коррекции эндотоксикоза при остром перитоните (обзор литературы)
//Research Focus. – 2022. – Т. 1. – №. 2. – С. 144-150.
5.
Саттаров Ш. Х., Рузибаев С. А., Хурсанов Ё. Э. Результаты лечения
острого разлитого гнойного перитонита с применением лапаростомии
//Research Focus. – 2022. – Т. 1. – №. 2. – С. 238-242.
6.
Шамсиев А. М. и др. Спектр микрофлоры при распространенном
аппендикулярном перитоните у детей //Детская хирургия. – 2020. – Т. 24.
– №. S1. – С. 94-94.
7.
Davlatov S. S., Kasimov S. Z. Extracorporal technologies in the treatment of
cholemic intoxication in patients with suppurative cholangitis //The First
European Conference on Biology and Medical Sciences. – 2014. – С. 175-179.
SCIENCE AND INNOVATION IN THE
EDUCATION SYSTEM
International scientific-online conference
114
8.
Davlatov S. S., Kasymov Sh. Z., Kurbaniyazov Z. B., Rakhmanov K. E.,
Ismailov A. O. Plasmapheresis in the treatment of cholemic endotoxicosis//
«Academic Journal of Western Siberia». - 2013. - № 1. - Р. 30-31.
9.
Kasymov S. Z., Davlatov S. S. Hemoperfusion as a method of homeostasis
protection in multiple organ failure syndrome // Academic Journal of Western
Siberia. – 2013. – Т. 9. – №. 1. – С. 31-32.
10.
Rakhmanov K. E. et al. The treatment of patients with major bile duct
injuries // Academic Journal of Western Siberia. – 2013. – Т. 9. – №. 1. – С. 33-34.
