No. 3 (102) (2018) Problems of biology and medicine

Статьи

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  Description of factors affected negatively on vision abilities of pupils and academic students The object of the study was investigation of factors affected on vision ability of school and academic stu-dents. It was found that among students is very low level of knowledge about elementary eye hygiene. The rea-sons for losing the vision ability among student population are spending a lot of time in front of TV and com-puter, doing homework in the dark evening hours, etc

  Х Nuralieva, Sh Yuldasheva

  63-65

  195   18

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  The use of radioisotopes for the diagnosis and therapy of various cancers Among the methods of physics used in modern medicine, methods based on nuclear technologies are becoming increasingly important. More than half (significant part) of oncological patients are currently cured with the use of remote or contact radiotherapy [4, 10].

  N Sodikov, Sh Khudaikulova, M Sodikov, F Temirov

  203-205

  92   25

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  Influence of alcohol influence on the peculiarities of the curve of brain-brain trauma Alcoholic intoxication leads to more severe injuries: those who suffer from alcohol intoxication. Mor-tality in patients with severe craniocerebral injury reaches 30%. The time of recurrence of cerebral and focal symptoms with a combination of trauma with alcohol intoxication is longer than in sober patients, on average by 28-30%.

  O Hwan, T Zikrillaev

  104-106

  146   28

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  Surgical aspects treatment of chronic colostases in children tional examination complexes were carried out. Various organic causes were identified, due to anatomical, muscular and functional disorders of the distal (large intestine) LI and their results were generally assessed in the ball system. In this case, the total, over 12 points and conservative treatment is ineffective, the relative indi- cations to the operation were determined. If more than 18 points, and revealed additional bends, lengthening, narrowing, incomplete fixation, rotation and rigidity of the LI, with clinical complete violations of the motor- evacuation function of the LI, direct indications for surgical treatment were determined. 162 (86%) patients had good results from complex conservative treatment. In 26 (14%) patients, indications for surgical treatment were determined with: no effect of prolonged ongoing conservative treatment, an increase in the phenomena of chronic colonic obstruction with decompensated flow and a progressive worsening of the patient's condition. When choosing the methods of operation, the age of the patients, the nature and localization of the pa- thology of the LI were taken into account. In children under 3 years, the Delatorre-Mandragon method was performed by transanal access; preschool-age method - Soave-Lenyushkin's method with abdominal perineal and in older children - resection and fixation of TK with laparatomy access. The nature of the operation was: resection of the elongated or narrowed LI zone with the creation of "colo-anal" or "colo-colo" anastomoses with fixation of pubescent "transversogastropexy" and rotated parts of the intestine in order to restore normal anatomical structures and transient functions of it. Complications in the early postoperative period was not noted.

  A Khamraev, U Mirzakhmedov

  98-103

  126   33

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  Chronic pain syndrome in diseases of the peripheral nervous system We have examined 146 patients, 71 patients with radiculopathy, 20 with plexopathy, 23 with compres- sion-ischemic neuropathies, 32 with chronic diabetic polyneuropathy. For this study we used the following methods: MRI, CT, X-ray, DN 4 questionnaire, electroneuromyography, Spielberger–Khanin questionnaire, Montgomery-Asberg depression rating scale, asthenia scale (MFI-20). The study showed that the clinical pic-ture, narure and severity of chronic pain syndrome in diseases of the peripheral nervous system does not di- rectly depend on the degree of damage to the peripheral nerves, being determined by the degree of central mechanisms of somatosensory system regulation involvement in the pathological process

  M Khamidullayeva, S Sattarova, P Gaffarova, S Khakimova

  95-97

  110   21

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  Effect of allogernioprosthetics of ventral hernias on the quality of life of patients The quality of life parameters of operated patients with ventral hernia of the abdominal wall by alloher-nioprosthetics with propylene filament during the first year after surgical intervention proved to be significant-ly better in a number of criteria in comparison with the QOL of patients whose hernioplasty was performed using inert sutures. These data coincided with the results of surgical treatment in the main and control groups of patient

  B Khamdamov, I Mirkhodzhaev, J Khikmatov, A Khamdamov

  92-94

  110   20

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  Quality of life and sleep related with chronic non-bacterial prostatitis versus benign prostatic hyperplasia The quality of life and sleep was determined in 80 sick on the outpatient setting: 47 men with chronic non-bacterial prostatitis (CNP) versus 33 men with benign prostatic hyperplasia (BPH). Quality of life was evaluated using the EuroQol-5D questionnaire. Quality of sleep was analyzed by Somnology Center question-naire. Pain evaluation in both groups was performed by Visual Analog Scale (VAS). Prostate-specific symp-toms were assessed using I-PSS and NIH-CPSI questionnaires. Patients with chronic pelvic pain and lower urinary tract symptoms showed significant disturbances in the quality of life and sleep. In CNP group those were connected with chronic pain syndrome, whereas in BPH group – predominantly with frequent urination and subsequent need of waking at night

  A Fedoruk, M Stepanchenko, V Romanenko

  86-91

  240   26

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  Exercise of a small pelvis with one-dimensional plastic the base of the base of the base the nearest results The study analyzed the immediate results after a front pelvic exenteration with a one-stage pelvic floor osteoplasty in 28 patients with locally advanced cervical cancer (MR cervical cancer) with a bladder germination with stage T2b-4N0-1M0. The age of patients ranged from 35 to 60 years, the average age was 47.5 years. The reasons that have a significant impact on the development of postoperative complications, the advantages of pelvic floor plastic, which reduces the incidence of postoperative complications, are analyzed

  M Tillyashaikhov, N Zakhirova, O Ahmedov, Е Boyko

  82-85

  145   30

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  Features of the development of heart failure in dilated cardiomyopathy in patients hospitalized in the hospital emergency medical care Dilated cardiomyopathy is a disease of the myocardium, characterized by a progressive increase in the size of the heart chambers and a decrease in myocardial contractility; it is the most common cause of severe heart failure, in which, subsequently, heart transplantation is required. The incidence of the disease in the pop-ulation is about 36.5: 100 000 population. In 20-30% of cases, DCMP is of a family nature. Most often, DCM is diagnosed already with the development of heart failure

  E Tashkenbayeva, G Sunnatova, G Majidova, S Ellamonov, Yu Sharapova, E Abdinova

  79-81

  110   21

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  Anosognasia in patients with acute period of ischemic blood-stroke In acute period of ischemic blood stroke, 80 patients were examined to establish co-relation of frequency neurological and neurophysiological symptoms. During examination were used following methods: MRT, CT, NIHSS scale and “Anosognosia Score”. In result of research were diagnostocated that patients in acute period of ischemic blood-stroke who had cognitive and excitor anosognasia with dysplasia of neurologic and motor disfunction compare to patients who had better self control developed more severely

  S Sattarova, M Khamidullayeva, P Gaffarova, S Khakimova, I Mamurova

  76-78

  108   20

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  Evaluation of the effectiveness of complex treatment of herpetik keratoconjunctivitis with the use of ozone through orion-si glasses We examined 26 patients (26 eyes) with herpetic keratitis in age from 17 to 63 years. Men were - 15, women - 11. A study group comprised 14 patients (14 eyes) who used traditional conservative therapy with the use of ozone therapy and the control group consisted of 12 patients (12 eyes) who used only the traditional medical therapy. As a result of comparative clinical studies and the comprehensive application of the method of ozone therapy and traditional medical treatment of herpetic keratitis showed that combined application allows you to increase the effectiveness of treatment, improves clinical outcomes.

  D Sabirova, M Yusupova

  74-75

  94   26

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  Chronorhythms secretory ig a in patients with chronic purulent maxillary sinusitis It was found that secretory IgA level in maxillary exudate has significantly day-night periodity. Two points of maximum level were indicated at 6.00 a.m. and 3.00 p.m. At the same time minimum level was found at 10.00 a.m. and 9.00 p.m. The investigation of proteolytic, fibrinolytic activity; activity of oxide-renewing processes are presented complex negative influence on secretory IgA production in cases of chronic purulent maxillary sinusitis in determined hours. Received results will serve one of the criterions at development of chronotherapeutic therapy in chronic purulent maxillary sinusitis treatment

  A Plaksiviy, I Kalutsky, O Masuria, K Yakovets, V Dzyubenko

  70-73

  63   24

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  Status fibrinolytic activity of exudate in patients with chronic purulent maxillary sinusitis in a comprehensive treatment using thiotriazoline The peculiareties of the tiotriasolinum influence on the exudate fibrinolytic activity of maxillary sinuses with local and general application in a multimodality therapy of patients with chronic purulent maxillary sinus-itis have been studied. A standard couse of treatment without tiotriasolinum application (control group) has been carried out in 20 patients with chronic purulent maxillary sinuses and in 43 patients the treatment has been combined with a local and general application of tiotriasolinum. It has been established that the total fi-brinolytic activity was significantly reduced in the process of treatment. Tiotriasolinum application probably decreased non-enzymatic fibrinolysis in total exudate fibrinolytic activity of maxillary sinuses and shortened the term of treatment

  A Plaksiviy, I Kalutsky, O Masuria, K Yakovets, O Ludin

  66-69

  59   23

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  Regional reasons of the extrahepatic subtransaminazemiya Results of retrospective and prospective analyses of the reasons of 117 cases of "a subtransami-nasaemia" (ST) of an extrahepatic origin are given in work. The range of the reasons of development of ST was very various. Thus diabetic mellitus, drug intake, dislipoproteinaemia and obesity are dominated. In this "quar-tet" the leading position of the induced ST by drug was taken.

  U Abdullayeva

  8-10

  59   16

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  To assessing the severity of radiographic changes in the neonate with respiratory distress syndrome X-ray examination of 100 newborns was carried out, 50 of them were newborns and 50 were premature infants with grade I and II prematurity. Newborn children born with syndrome of respiratory disorders (SRD) require special attention from the first days of illness and professionally competent medical tactics. At X-ray examination of premature newborns with pneumonia, the predominance of SDR characteristic features was observed. Refinement of the degree of severity of the SDR of the newborn with pneumonia allows the most ac-curate and objective assessment of the severity of the sick child. The results of X-ray studies of pneumonia in newborns allow us to conclude that they need to be carried out in the neonatal period. The X-ray method for assessing the degree of severity of SDS in pneumonia of newborn infants, especially premature infants, and with intrauterine growth retardation syndrome is convenient for its non-invasiveness, minimal radiation expo-sure to the subject, a wide range of indicators and information rich in morphology, which contributes to the timely correction of complex treatment, especially at the risk of SDR, reducing the development of posthypoxic complications of the adaptation period.

  Sh Narzikulov, G Mardieva, M Abdullayeva, A Khurramov

  60-62

  132   29

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  Analysis of the results of surgical treatment of posttraummatic scarring structures of the main bile ducts This work is based on the experience of treating 153 patients operated in connection with posttraumatic cicatricial strictures of the hepatic ducts (134-87.6%), as well as with cicatricial stenoses of biliodigestive anastomoses (19 - 12.4%), formed earlier due to trauma hepatitis choledoch in the period from 2007 to 2017. The tactics of treatment of strictures of the hepatic ducts made it possible to obtain good results in 55.3% of the observations from the total number of patients traced in the long-term period. Relapse of the disease occurred in 44.7% of patients. Repeated operation allowed satisfactory results in 64.7% of this category of patients or in 28.9% of the total number of observations. Ultimately, the overall percentage of good and satisfactory results is 84.2%, the incidence of unsatisfactory results and mortality in the long-term period is 15.8%, respectively

  F Nazyrov, Z Kurbaniyazov

  53-59

  118   15

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  Structural changes in aponeuroses in patients with postoperative ventral hernias of different age groups Objective of the study. To determine the structural differences of aponeuroses in different age groups of patients with postoperative ventral hernias. Materials and methods. Comparative orphological studies of aponeuroses of 36 patients operated in the First and the Second hospitals Samarkand State Medical Institute for postoperative ventral hernias aged 40 to 76 years. Patients are divided into 3 groups according to the WHO age classification: Group I included patients 45-59 years old; Group II 60-74 years old; and the Group III in-cluded patients 75-90 years old. The biopsy specimens of the anterior abdominal wall, obtained during hernio-plasty were subjected to histological examination. Standard pieces of aponeurotic abdominal wall tissues taken during surgery were fixed in a 10% formalin solution on phosphate buffered saline for light microscopy exami-nations. Paraffin sections were stained with hematoxylin and eosin (H&E). Results. Investigation of biopsy specimens of aponeuroses and adjacent muscle tissue in patients of different age groups have revealed signifi-cant structural differences that can determine the frequency of hernias of the anterior abdominal wall and their recurrences. Conclusions. The study discovered that with advancing age significant structural changes occur on the aponeurosis of abdominal rectal muscles. The nature of these changes, especially the disruption of the collagen fiber arrangements, suggests that these structural changes are responsible for the weakening of the aponeurosis.

  F Nazyrov, A Shamsiev, I Baibekov, O Eshonkhojaev, S Davlatov

  47-52

  225   28

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  Autism in children and its influence on the somatic and neurologic status In the structure of somatic pathology in children with autism, GI diseases, allergic and immunopatholo-gy are significantly more often diagnosed. Neurological status in them was characterized by diffuse micro-symptomatics in the form of dissociation of tone, changes in reflexes (mild asymmetry of tendon and periosteal reflexes), low speech production and the presence of a defect in social communication

  YA Majidova, F Doniyorova, N Ergasheva

  44-46

  104   25

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  Violation of vascular – platelet phase of hemostasis in patients with chronic hepatitis and liver cirrhosis of the viral etiology There are thrombocytopenia, infringement of adhesive and aggregating properties of thrombocites in liver cirrhosis of a viral etiology. The decrease activity of the vascular – platelet part of the coagulation system was more pronounced in patients with viral liver cirrhosis compared with non - viral liver cirrhosis. Cirrhosis of the C viral etiology was accompanied by more significant changes in the process of hemocytopoiesis in the bone marrow, but signs of hypersplenism prevailed in liver cirrhosis В or В+Д viral etiology

  Z Kurbonova

  40-43

  137   30

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  Bacterial vaginosis - the problem of modern wonen The article are presented definitions of the vaginal microflora in norm and diseases, such as bacterial vaginosis and colpitis. Today, there is much methods for normalization vaginal microflora. Objectives. The complex studies a condition of vaginal microbiocenosis in women with diagnosed of bacterial disbiosis and compare efficiency intravaginal preparations containing metronidazole + miconazole and ascorbic acid. 48 female patient with diagnosis bacterial vaginosis are participated in the study. The results showed that in 85% the improvement was for women who used intravaginal introduction metronidazole + miconazole, than at women who applied ascorbic acid which has made 50%.

  M Kurbaniyazova

  36-39

  114   28

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  Prenatal tactics of ultrasonic federation in the early period of pregnancy In order to avoid undeveloped pregnancy, and intrauterine fetal death, as well as early detection of fetal malformations, there is a need for screening in the first trimester of pregnancy. Inclusion of the first trimester in the screening program in a timely manner will create risk groups for the birth of children with malfor-mations of the fetus, timely resolve the issue of further introduction of pregnancy, thereby reducing obstetric complications, and also reduce maternal and infant mortality

  Sh Kamalidinova, G Azimova

  30-35

  128   27

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  The features of clinical-endoscopic manifestations of nsaid inducted gastroduodenopathies This article presents the results of clinical and endoscopic studies of 64 patients with NSAIDs (non- steroidal anti-inflammatory drugs)-induced gastroduodenopaties. In the first group of patients who had a histo-ry of the disease gastrointestinal tract and who took NSAIDs dyspeptic symptoms such as heartburn, nausea, vomiting, epigastric pain and sternal areas were more pronounced than in the second group, where no history gastroduodenal diseases. Along with this data EGDS were also more pronounced in the first group of patients than with respect to the second

  N Isamitdinova

  27-29

  61   18

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  Reconstruction of the base bottom after the exercise of a small pancre with a locally distributed cancer The study analyzed the results of treatment in a comparative aspect after a front pelvis exenteration with a single-stage pelvic floor plastic surgery in 88 patients with locally advanced cervical cancer (MR cervical cancer) with stage T2b-4N0-1M0 disease. An assessment of the possibilities and advantages of plastic recon-struction of the pelvic floor has been made, which reduces the incidence of postoperative complications

  N Zakhirova, М Tillyashaikhov, O Ahmedov, Е Boyko

  23-26

  129   26

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  Balanced field block anesthesia on the basis of prolonged conducting blockade of the humeral texture at children Efficiency of the balanced field block anesthesia on the basis of prolonged conducting blockage of bra-chial plexus was learned involving 121 patients, aged between 2 and 14 years with upper extremities traumas. The given algorithm of the balanced field block anesthesia on children with 0,25% bupivacaine and intraopera-tive sedation (ketamin+dormicum), provide an adequate intraoperative anesthesia and the long-term highly-effective postoperative analgesia, on average 10 hours in 95.2% cases

  T Zakirov, M Sharopova, Sh Yarikulov

  18-22

  104   34

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  The importance of vitamin d in the development of reproductive healt of women of young fertile age The effects of a reduction of vitamin D to the fertile ages of young woman's immune system have been learnt. The reduction of vitamin D causes for the rise of risk in the case of development of gynecological illnis-ses of vagine like heterospecific inflammatory as well as dishormonal and chronic pielonefritis diseases

  B Jumanov, Sh Zufarova, K Azimova

  129   22

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