424
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
LIPIDS OF THE AERIAL PARTS
OF ARTEMISIA ANNUA
L.
1
Normakhamatov N.S.
1
A.A. Turaboev
1
Ch.T.Toshtemirova
2
F.A.Kodiralieva
2
A.A.Siddikova
1
Tashkent Pharmaceutical Institute, Tashkent, Uzbekistan
2
Institute of Plant Chemistry named after Academician S. Yu. Yunusov
Academy of Sciences of the Republic of Uzbekistan, Tashkent. Uzbekistan
https://doi.org/10.5281/zenodo.17341469
Relevance:
Lipids of medicinal plants are of interest as a source of biologically active
compounds.
Artemisia annua
L. (annual wormwood) is known for its antimalarial and anti-
inflammatory properties, but the lipid composition of its aboveground parts has not been sufficiently
studied.
The aim of the study:
To determine the content, composition and fatty acid profile of neutral
and polar lipids of the aboveground part
of Artemisia annua
L.
Materials and methods:
Air-dried above-ground part of
Artemisia annua
L. Neutral lipids
were isolated by extraction with gasoline (b.p. 75–80 °C). Polar lipids were extracted using the Folch
method with a mixture of chloroform and methanol (2:1 v/v) and purified with a 0.04% CaCl 2
solution . The component composition was determined by TLC. The fatty acid composition was
determined by gas chromatography ( Agilent 6890N).
Results:
Lipid content is shown in Table 1.
Table 1. Lipid characteristics of the aboveground part
Artemisia annua L .
Indicator
Content
1. Moisture, % of the weight of the above-ground part
8.6
2. Total lipids, % of the weight of the aboveground part, including:
2a. Neutral lipids, %
2b. Polar lipids, %
5.89
4.34
1.55
3. Content, mg/l: chlorophyll “ a ”
chlorophyll " b "
1.5
0.5
Component composition: NL contain hydrocarbons, fatty acid esters with phytosterols and
triterpenols , triacylglycerides , free fatty acids and alcohols, triterpenols , phytosterols , chlorophyll
pigments.
PL are represented by glycolipids and phospholipids.
The fatty acid composition according to (GC) is given in Table 2
Table 2. Fatty acid composition of the aboveground part
of Artemisia annua L.
GC, % of the
mass of acids
No.
Fatty acid
Samples
NL
PL
1
Linoleic , 18 :2
41,2
35.1
2
Oleic, 18 : 1
20.5
10.5
3
α - Linolenic, 18 : 3
7.9
5.7
4
Palmitic, 16:00
18.4
14.9
425
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
5
Linolenic, 18 : 3
1.7
24.9
6
Stearic, 18:0
3.5
2.2
7
Myristic , 14:0
2.2
1.5
8
Arachinovaya , 20:00
1.5
1.7
9
Eicosene , 20:1
1.8
1.0
10
Begenova , 22:00
1.3
1.9
Σ
saturated fatty acids
26.9
22.2
Σ
unsaturated fatty acids
73.1
77.2
Conclusions :
• Lipids of the aboveground part
of Artemisia annua
L. are rich in unsaturated
fatty acids (73.1% in NL, 77.2% in PL).
• Essential acids: linoleic , oleic, linolenic, palmitic.
• The data obtained expand the knowledge about the chemical composition
of Artemisia annua
and can be used to develop pr preparations and functional products.
