The purpose of the study is to study the sensitivity of microbes to certain drugs in vitro! Material and Methods: to establish this research method, we have prepared 18-hour cultures of microbes - taking into account the most frequent inhabitants in the oral cavity. 1-2 ml of the studied microbes were applied to the surface of the dried nutrient medium by Mueller Hinton. The preparation sea buckthorn oil had an antibacterial effect on most microbes, although among them the most sensitive were such microbes as streptococci, proteas and pseudomonas. At the same time, the chlorhexidine drug had an effect on most microbes, but the effect was insignificant and only streptococci were the most sensitive and amounted to 18.0 ± 0.3 mm. Conclusions: the drugs used to treat sick children belonging to the group of traditional therapy have a weak antibacterial effect. At the same time, drugs from the special treatment group have a more pronounced antibacterial effect, especially on microbes of the genus streptococci.
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