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COMBINATION OF DIABETES AND METABOLIC SYNDROME
Jo’rayeva Gulhayo Jalol qizi
Asian International University
https://doi.org/10.5281/zenodo.14528640
Abstract.
This article provides an overview of the relationship between type 2 diabetes and
metabolic syndrome.
Key words:
Type 2 diabetes, metabolic syndrome, pancreas, B-cells, insulin resistance,
glucose, triglycerides, obesity, polyuria, polyphagia, headache, blurred vision, nervousness.
СОЧЕТАНИЕ ДИАБЕТА И МЕТАБОЛИЧЕСКОГО СИНДРОМА
Аннотация.
В этой статье представлен обзор взаимосвязи между диабетом 2
типа и метаболическим синдромом.
Ключевые слова:
диабет 2 типа, метаболический синдром, поджелудочная железа,
В-клетки, инсулинорезистентность, глюкоза, триглицериды, ожирение, полиурия,
полифагия, головная боль, нечеткость зрения, нервозность.
Introduction:
The type of diabetes that is called an invisible epidemic in the world is
increasing day by day. This can also be seen from the average number of doctors. Unfortunately,
as evidenced by the fact that it is twice as high to occur in this high age group as well. Type 2
Diabetes Causes Obesity.
Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose
(or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys
and nerves. The most common is type 2 diabetes, usually in adults, which occurs when the div
becomes resistant to insulin or doesn't make enough insulin. In the past 3 decades the prevalence
of type 2 diabetes has risen dramatically in countries of all income levels.
Obesity, especially when associated with increased abdominal and visceral fat distribution
and increased intrahepatic and intramuscular triglycerides, is a major risk factor for prediabetes
and type 2 diabetes. , because it causes insulin resistance and β-cell dysfunction.
Dietary fat does not immediately affect blood sugar levels, but eating fatty foods can slow
down digestion and make it harder for insulin to work properly.
The task of B-cells produced by the pancreas is to reduce the amount of glucose in the
blood. When there is too much glucose in the blood, the div may try to pass it through the urine.
Dehydration occurs in the div. The higher the blood sugar level, the more frequent the headache.
In addition, vision deteriorates. Due to the lack of insulin, glucose accumulates in the blood, does
not enter the cells and does not participate in energy production. Therefore, the patient always
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feels hungry. Without glucose in the cells, not enough energy is produced. As a result, fatigue
increases in the div. You don't have enough energy for the tasks you have done before. Diabetes
mellitus is a disease characterized by the inability of glucose, the main source of energy, to enter
the cells, and metabolic processes in the div begin to malfunction. As a result, insulin levels
decrease and blood sugar increases.
Materials and methods
Type 2 diabetes develops slowly. There is also an asymptomatic type of the disease.
constant dry mouth, constant thirst, sometimes the patient can drink seven to ten liters of
water a day;
• a lot and frequent urination (polyuria);
• increased appetite (polyphagia);
• soreness/itching/dryness of the skin and soft tissues, the appearance of purulent ulcers on
the skin and soft tissues;
• severe fatigue, insomnia, decreased physical and mental activity;
• deterioration of vision;
Metabolic syndrome is a group of factors that increase the risk of developing
cardiovascular disease and type 2 diabetes.
• Metabolic syndrome is diagnosed when at least three of the following five factors are
present:
1. Increase in waist circumference: (more than 102 cm for men and 88 cm for women).
2. High blood pressure (systolic ≥130 mm Hg or diastolic ≥85 mm Hg).
3. Elevated triglyceride levels (≥150 mg/dL).
4. Decreased high-density lipoprotein (HDL) levels (less than 40 mg/dL for men and less
than 50 mg/dL for women).
5. Increased fasting blood glucose (≥100 mg/dL).
• Causes and risk factors
Obesity
Insulin resistance
Genetic predisposition
Malnutrition (increasing calories, fats and carbohydrates)
Lack of physical activity
Age and gender
Consequences of metabolic syndrome
Increased risk of cardiovascular diseases (myocardial infarction, stroke).
Development of type 2 diabetes
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Liver diseases (fatty liver disease)
Kidney problems
Obesity is a disease characterized by excessive accumulation of adipose tissue in the
subcutaneous adipose tissue, abdomen, chest and other areas of the div.
How obesity occurs
• Obesity occurs as a result of an imbalance between the energy content of the food
consumed and the energy used by the div, that is, excess energy is accumulated in the form of
low energy and high energy consumption. accumulation of fat in different parts of the div.
• The human div is evolutionarily adapted to store food when it is sufficient, and to
expend it when food is scarce. However, its excessive accumulation and lack of consumption leads
to disease.
• The most common causes of obesity are inactivity, poor diet and genetic factors.
• Obesity occurs as a result of an imbalance between the energy content of the food
consumed and the energy used by the div, that is, excess energy is accumulated in the form of
low energy and high energy consumption. accumulation of fat in different parts of the div.
• The human div is evolutionarily adapted to store food when it is sufficient, and to
expend it when food is scarce. However, its excessive accumulation and lack of consumption leads
to disease.
• The most common causes of obesity are inactivity, poor diet and genetic factors.
So, if you have diabetes, hyperinsulinemia, high cholesterol or high blood pressure, you
should be under the supervision of a doctor to control these diseases. Exercise and weight loss are
key to improving insulin sensitivity and lowering blood pressure and cholesterol levels.
Conclusion
: If we pay attention to the above signs, we will detect type 2 diabetes early.
By taking timely measures against metabolic syndromes, we can prevent type 2 diabetes.
REFERENCES
1.
Rajabova Oygul Islomovna.(2024). VIRUSLI GEPATITLAR VA TUG‘RUQDAN
KEYINGI
ERTA
QON
KETISHLARNI
KAMAYTIRISHNING
YANGI
TEXNOLOGIYALARI. ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ, 39(5), 99–106.
https://www.newjournal.org/index.php/01/article/view/11723
2.
Rajabova Oygul Islomovna .(2024). A Comparative Analysis of the Effectiveness of
Vaginal Progesterone, Cervical Pesar, and Their Combination for Preventing the Risk of
Premature Labor in High-Risk Pregnant Women BEST JOURNAL OF INNOVATION IN
SCIENCE,
RESEARCH
AND
DEVELOPMENT,
3(3),
440-446.
http://www.bjisrd.com/index.php/bjisrd/article/view/1849/1700
694
ResearchBib IF-2023: 11.01, ISSN: 3030-3753, Valume 1 Issue 10
3.
Rajabova Oygul Islomovna.(2024). MODERN CONCEPT OF RECURRENT VAGINAL
INFECTIONS
IN WOMEN OF REPRODUCTIVE AGE, 3(04), 128-131.
https://jhlsr.innovascience.uz/index.php/jhlsr/article/view/518/455
4.
Rajabova Oygul Islomovna.(2024).
METHODS OF PHARMACOTHERAPEUTIC
TREATMENT OF ABNORMAL UTERINE BLEEDING IN GIRLS, 3(5),193-197
https://mudarrisziyo.uz/index.php/pedagogika/article/view/945
5.
Rajabova Oygul Islomovna.(2024).
Method Stopping Atonic Bleeding From the Uterus
after Childbirth Using Balloon Tamponade
International Journal of Alternative and
Contemporary Therapy with U.S. ISSN 2995-5378
In Volume 2, Issue 9 (2024)
https://medicaljournals.eu/index.php/IJACT/article/view/965
6.
Rajabova Oygul Islomovna.(2024).
Tactics for carrying women at high risk of recurrent
miscarriage.
New renaissance journal ResearchBib IF-2023: 11.01, ISSN: 3030-3753,
Valume 1 Issue 8 Pp:509-514
https://doi.org/10.5281/zenodo.13982730
7.
Farida Farkhodovna, K. ., Umida Rakhmatulloevna, N. ., & Mokhigul Abdurasulovna, B.
(2022). ETIOLOGY OF CHRONIC RHINOSINUSITIS AND EFFECTIVENESS OF
ETIOTROPIC TREATMENT METHODS (LITERATURE REVIEW). Новости
образования: исследование в XXI веке, 1(4), 377–381. извлечено от
https://nauchniyimpuls.ru/index.php/noiv/article/view/1367
8.
Numonova,
A.,
&
Narzulayeva,
U.
(2023).
EPIDEMIOLOGY
AND
ETIOPATHOGENESIS OF CHF. Наука и инновация, 1(15), 115-119.
9.
Орипова Озода Олимовна, Самиева Гулноза Уткуровна, Хамидова Фарида
Муиновна, & Нарзулаева Умида Рахматуллаевна (2020). Состояние плотности
распределения лимфоидных клеток слизистой оболочки гортани и проявления
местного иммунитета при хроническом ларингите (анализ секционного материала).
Academy, (4 (55)), 83-86.
10.
Umida Rakhmatulloevna Narzulaeva, & Xamrayeva Muxlisa Farmon qizi. (2023).
ETIOPATHOGENESIS OF HEMOLYTIC ANEMIA. Web of Medicine: Journal of
Medicine,
Practice
and
Nursing,
1(1),
1–4.
Retrieved
from
https://webofjournals.com/index.php/5/article/view/26
11.
Нарзулаева, У., Самиева, Г., & Насирова, Ш. (2023). Гемореологические нарушения
на ранних стадиях гипертензии в жарком климате. Журнал биомедицины и
практики, 1(1), 221–225.
https://doi.org/10.26739/2181 -9300-2021-1-31
12.
Umida Rakhmatulloevna Narzulaeva. (2023). Important Aspects of Etiology And
Pathogenesis of Hemolytic Anemias. American Journal of Pediatric Medicine and Health
695
ResearchBib IF-2023: 11.01, ISSN: 3030-3753, Valume 1 Issue 10
Sciences
(2993-2149),
1(7),
179–182.
Retrieved
from
https://grnjournal.us/index.php/AJPMHS/article/view/817
13.
Нарзулаева, У. Р., Самиева, Г. У., & Насирова, Ш. Ш. (2021). ИССИҚ ИҚЛИМДА
КЕЧУВЧИ ГИПЕРТОНИЯ КАСАЛЛИГИНИНГ БОШЛАНҒИЧ БОСҚИЧЛАРИДА
ГЕМОРЕОЛОГИК БУЗИЛИШЛАР. ЖУРНАЛ БИОМЕДИЦИНЫ И ПРАКТИКИ,
6(1).
14.
Нарзулаева, У., Самиева, Г., Лапасова, З., & Таирова, С. (2023). Значение диеты в
лечении артериальной гипертензии . Журнал биомедицины и практики, 1(3/2), 111–
https://doi.org/10.26739/2181-9300-2021-3-98
15.
Narzulaeva Umida Rakhmatulloevna, Samieva Gulnoza Utkurovna, & Ismatova Marguba
Shaukatovna (2020). SPECIFICITY OF THE CLINICAL COURSE OF THE INITIAL
STAGES OF HYPERTENSION IN ARID ZONES OF UZBEKISTAN AND NON-
DRUG APPROACHES TO TREATMENT. Кронос, (4 (43)), 15-17.
16.
Umida Raxmatulloevna Narzulaeva, & Mohigul Abdurasulovna Bekkulova (2023).
Arterial gipertenziya etiologiyasida dislipidemiyaning xavf omili sifatidagi roli. Science
and Education, 4 (2), 415-419.
17.
Narzulaeva, U. R., & Samieva, G. U. (2021). Nasirova ShSh. Hemoreological Disorders in
The Early Stages Of Hypertension In Hot Climates. Journal of Biomedicine and Practice,
6(1), 221-225.
18.
Dilsora Nuriddinovna Juraeva, Umida Rakhmatulloevna Narzulaeva, & Kurbonova
Gulbahor Aslamovna. (2022). GENDER DIFFERENCES IN THE PARACLINICAL
FEATURES OF THE COURSE OF TRIGEMINAL NEURALGIA. World Bulletin of
Public
Health,
8,
186-190.
Retrieved
from
https://www.scholarexpress.net/index.php/wbph/article/view/751
19.
Narzulaeva, U. (2023). PATHOGENETIC MECHANISMS OF MICROCIRCULATION
DISORDERS. International Bulletin of Medical Sciences and Clinical Research, 3(10),
60–65. Retrieved from
https://researchcitations.com/index.php/ibmscr/article/view/2811
20.
Narzulaeva Umida Rakhmatulloevna and Rakhmatova Fotima Ulugbekovna,
“PATHOGENETIC MECHANISMS OF DISORDERS IN THE HEMOSTASIS
SYSTEM OBSERVED IN PATIENTS INFECTED WITH COVID-19”, IEJRD -
International Multidisciplinary Journal, vol. 7, no. ICMEI, p. 3, Feb. 2023.
21.
Rajabova Oygul Islomovna.(2024). ASSESSMENT OF THE FREQUENCY OF
CAESAREAN SECTION USING ROBSON'S CLASSIFICATION IN MATERNITY
INSTITUTIONS (EXAMPLE OF PERINATAL CENTER OF BUKHARA REGION).
696
ResearchBib IF-2023: 11.01, ISSN: 3030-3753, Valume 1 Issue 10
ResearchBib
IF-2023:
11.01,
ISSN:
3030-3753,
Valume
1
Issue
9
https://doi.org/10.5281/zenodo.14182279
22.
Shukurova, S. (2024). Optimizing synergies: Effective strategies for integrating economic
and environmental interests in sustainable development. In E3S Web of Conferences (Vol.
587, p. 04007). EDP Sciences.
23.
Tuyg’unovna, S. S. (2024). MEDICINAL PLANTS THAT ARE WIDELY USED IN
NATURE, RICH IN VITAMINS. ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ
ИДЕИ В МИРЕ, 39(3), 242-247.
24.
Tuyg’unovna, S. S. (2024). THE PROCESS OF PACKAGING MEDICINAL PLANTS.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 39(3), 248-256.
25.
Tuyg’unovna, S. S. (2024). ABOUT USEFUL MEDICINAL PLANTS RICH IN LIPIDS
USED IN MEDICINE.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В
МИРЕ
,
39
(3), 235-241.
26.
Tuyg’unovna, S. S. (2024). TARKIBIDA EFIR MOYLAR BO’LGAN DORIVOR
O’SIMLIKLAR. TA'LIM VA RIVOJLANISH TAHLILI ONLAYN ILMIY JURNALI,
4(3), 164-167.
27.
Tuyg’unovna, S. S. (2024). MEDICINAL PLANTS CONTAINING ESSENTIAL OILS.
ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ, 41(4), 62-69.
28.
Tuyg’unovna, S. S. (2024). TARKIBIDA ALKALOIDLAR BO’LGAN DORIVOR
O’SIMLIKLAR. ОБРАЗОВАНИЕ НАУКА И ИННОВАЦИОННЫЕ ИДЕИ В МИРЕ,
41(4), 70-77.
29.
Tuyg’unovna, S. S. (2024). CULTIVATION OF MEDICINAL PLANTS AND FORMS
OF PREPARATION. EUROPEAN JOURNAL OF MODERN MEDICINE AND
PRACTICE, 4(5), 71-75.
30.
Tuyg’unovna, S. S. (2024). SYSTEMATIC ANALYSIS OF MEDICINAL
PLANTS.
Лучшие интеллектуальные исследования
,
19
(5), 159-164.
31.
Tuyg’unovna, S. S. (2024). DORIVOR O’SIMLIKLARNING SISTEMATIK TAHLILI.
TA'LIM VA RIVOJLANISH TAHLILI ONLAYN ILMIY JURNALI, 4(4), 180-184.
32.
Tuyg’unovna, S. S. (2024). BAKTERIYALAR GENETIKASI. BAKTERIYALARDA
GENETIK
ALMASHINUV
MIKROORGANIZMLARNING
O
‘ZGARUVCHANLIGI.
MASTERS
,
2
(5), 183-192.
