Study of the immune condition of the frequently sicked children invalid against hib

Haemophilus influenzae type b is one of the common causes of generalized infection (bacteremia) in children, half of them developed purulent meningitis, quite often (15-20%), pneumonia, and rarely other focal lesions. In countries where the vaccination campaign against Hib-infection, there is a decrease in morbidity and frequency carrier Hib. Vaccination, in these countries, has led to a decrease in carrier frequency in a population of healthy children up to 0.5-1.0%. However, vaccination coverage of infants, vaccine efficacy ACP-Hib, preservation of antibody titer in the infection and their comparison with the reduction of morbidity during the vaccination have not been investigated. Figuring allow them to improve preventive measures in organized and unorganized babies on Hib-infection and to assess their cost-effectiveness. All of the above was the object of study