HISTOPATHOLOGY OF BASAL CELL CANCER
Abstract
In the structure of malignant neoplasms of the skin, the first place belongs to basal cell cancer. A wide range of clinical manifestations, the complexity of differential diagnosis at the onset of the disease cause an in-depth interest in histological studies. The purpose of this article was to present a detailed analysis and morphological characteristics of the most common histological variants of BCR, both used in the modern WHO classification and already of historical interest. Along with the description of each variant of BCR, differential diagnostic histological signs and diagnoses with which they should be differentiated are given. It is shown that the variety of diseases with which differential diagnosis is required includes both neoplastic and inflammatory diseases. It is clear that there is a need for routine dermatological examination of patients, including clinical examination, non-invasive and invasive histological methods of skin examination, clinical and morphological correlation and, in some cases, immunohistochemical methods.
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Abstract
In the structure of malignant neoplasms of the skin, the first place belongs to basal cell cancer. A wide range of clinical manifestations, the complexity of differential diagnosis at the onset of the disease cause an in-depth interest in histological studies. The purpose of this article was to present a detailed analysis and morphological characteristics of the most common histological variants of BCR, both used in the modern WHO classification and already of historical interest. Along with the description of each variant of BCR, differential diagnostic histological signs and diagnoses with which they should be differentiated are given. It is shown that the variety of diseases with which differential diagnosis is required includes both neoplastic and inflammatory diseases. It is clear that there is a need for routine dermatological examination of patients, including clinical examination, non-invasive and invasive histological methods of skin examination, clinical and morphological correlation and, in some cases, immunohistochemical methods.
References
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