73
Volume 5, Issue 10: Special Issue
(EJAR)
ISSN: 2181-2020
MPHAPP
THE 6TH INTERNATIONAL SCIENTIFIC AND PRACTICAL
CONFERENCE
“
MODERN PHARMACEUTICS: ACTUAL
PROBLEMS AND PROSPECTS
”
TASHKENT, OCTOBER 17, 2025
in-academy.uz
DEVELOPMENT OF OBTAINING A DRY EXTRACT FROM THE HERB OF
EQUISETUM ARVENSE
Rakhimova O.R.
1
Lurye M.E.
2
Rakhimova G.R.
3
Tashkent Pharmaceutical Institute, Tashkent city, Republic of Uzbekistan
e-mail: oygulr@bk.ru
https://doi.org/10.5281/zenodo.17318872
Relevance:
the importance of marketing research on the diuretic pharmaceutical market is
determined by their key role in modern therapeutic practice. This group of drugs is widely used in the
treatment of such common conditions as arterial hypertension, chronic heart failure, edema of various
etiologies, and nephrological pathologies. One such plant, widely used in folk medicine, is horsetail
(Equisetum arvense). Horsetail infusions have a comprehensive effect on the div. They stimulate
the elimination of excess fluid, which helps manage swelling, and combat inflammation in the urinary
tract. Horsetail also has general tonic, hemostatic, healing, and astringent properties. It is effective
for cystitis, urethritis, and swelling caused by kidney dysfunction or heart failure.
Purpose of the study:
development of a rational method for obtaining a dry extract from
horsetail herb.
Materials and methods:
four methods were studied to obtain an alcoholic extract from
horsetail: maceration, fractional maceration, percolation, and repercolation. All of these methods are
standard in the industrial production of alcoholic extracts from plant materials. At the end of each
extraction step or the entire process, the resulting liquids were combined by gravity. The remaining
pulp was pressed, and the resulting extract was added to the corresponding extracts. The combined
extracts were then settled at a temperature below 10°C for two days and filtered.
For the experiment, dried plant material was ground to the desired fraction. The resulting
powder was dried in a rotary evaporator at 40-50°C. The study was conducted using standard
methods, beginning with determining the optimal process parameters for medicinal plant material and
culminating in establishing quality standards for the final product. The technological characteristics
of medicinal plant material include such parameters as the degree of grinding, particle size
distribution (fractional composition), bulk density (bulk density), solvent absorption capacity
(extractant absorption coefficient), and ease of movement (flowability). Also important are the time
required to extract the active substances (extraction duration) and the number of interactions between
the material and solvent (multiplicity). To determine the optimal degree of grinding, a quantitative
analysis of the total tannins in the experimentally obtained extracts was conducted. The quality of the
extracts was assessed based on the dry residue. Based on these data, the repercolation method was
chosen as the most effective.
Results:
the extraction yielded a dark-brown liquid product with a greenish tint and a distinct
odor. This liquid extract was then concentrated by vacuum evaporation on a rotary evaporator. The
final step involved vacuum drying to obtain a dry extract, a hygroscopic brown powder with a residual
moisture content of no more than 5% and a characteristic aroma.
Conclusions:
based on the dry residue content, the most optimal extraction method was chosen
– repercolation, and the most optimal extractant was 40% ethyl alcohol.
