All articles - Pediatrics
Number of articles: 1706
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Features of etiology, clinical course of acute allergic conditions in children living in an ecologically unfavorable region of the city of BukharaThe frequency of treatment of acute allergic conditions in an ambulance, children living in an ecological- ly unfavorable region of the city of Bukhara during the periods of 2001-2005, had a tendency to increase by 1.2 times (2.9-3.4%), and boys with the indicated states suffered almost 1.3 times more often than girls. Acute al- lergic conditions clinically manifested in the form of severe and moderate severity of the course of food allergy - 39.3%, allergic dermatitis - 18.1%, drug allergy - 12.5%, bronchial asthma - 10.2%, pollen and dust allergy - 10.1% and insect allergy - 9.8%. In the formation and development of acute allergic conditions, in addition to causative factors, such risk factors as hereditary burden - 70.3%, allergic diathesis - 60.5%, artificial feeding - 55.3% were of significant importance.
Journal problems of biology and medicine -
Study of the immune system of children with laryngeal papillomatosis on the background of antiviral therapyA comparative analysis of the immunological parameters in the dynamics (before and after) of standard therapy and after standard + immunotropic therapy was performed in 252 children with papillomatosis of the larynx at the age of 3 to 9 years who were on the examination and treatment in the surgical department of oto-rhinolaryngology TMA. in the state of immune response in laryngeal papillomatosis, unidirectional changes, most pronounced in children with continuously recurrent form of laryngeal papillomatosis, were revealed. In the dynamics of therapy, there was an improvement in the cellular and humoral immunity, improvement in the clinical state of children, and a decrease in the frequency of relapses.
Journal problems of biology and medicine -
Significance of hepatobiliary system in pathogenesis of dentoalveolar anomalies in schoolchildrenTo identify features of relationship between hepatobiliary system and dentoalveolar anomalies in children, the content of volatile fatty acids in saliva was studied. The study result revealed that combination of hepatobiliary system diseases in children with dentoalveolar anomalies has been a negative impact on biliary tract function, which was reflected not only in strengthening of dysfunctional disorders in bile rheology malfunction, but in threat of formation diseases such as chronic holecistoholangitis. In light of the above, it has been necessary to create conditions for normal functioning of liver cells, and thus entire hepatobiliary system, stabilization of cell membranes, providing bile physiological secretion, restoration of intercellular connections to normalize outflow of bile in children with functional disorders of hepatobiliary system associated with dentoalveolar anomalies.
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Syndrome of endogenous intoxication in children and its influence on the clinical currency of chronic rinosinusiti on the background of the chronic bronchitisThe development is due to the use of large doses of antibiotics, as this causes the death of a large number of pathogens and abundant entry into the blood of endotoxins, in which the severe condition of the body is ag- gravated by a sharp violation of hemodynamics, circulation and perfusion of tissues. In the pathogenesis of shock, the leading place is occupied by the violation of micro- and macrocirculation
Journal problems of biology and medicine -
Clinical-neurological examination and the results of neuroimaging of children with the consequences of craniocerebral traumaMRT date are presented for the study of children with craniocerebral trauma, in the initial and long-term period, depending on the clinical picture, paresis (hemiparesis, tetraparesis and so on). The obtained results of both diffuse and focal posttraumatic disorders in the central nervous system in patients with consequences of a moderate craniocerebral trauma
Journal problems of biology and medicine -
Author presented evaluation data of the computer brain neurosonography results and hemodynamic monitoring of the 56 newborns with hemorrhagic insult. At newborns with hemorrhagic insult were identified significant changes of the hemodynamic not only in the brain, but also of the whole organism, which is not always manifested in the clinical symptoms. It must be taken into account when treating newborns with hemorrhagic insult, especially during surgical interventions. -
Intellectual development of children with progressive muscular dystrophies of duchenne beckerThis article provides data on the evaluation of the intellectual development of children with progressive muscular dystrophy Duchenne / Beccre. It is established that 43% of children have intellectual insufficiency. The lower level of non-verbal intelligence, reduced ability for visual analysis and synthesis, intellectual exhaus- tion, low level of arbitrary control, difficulty in distributing attention and general infantilism in children with progressive muscular dystrophy of Duchesne came to the fore in the study. While in children with Becker's pro- gressive muscular dystrophy, intelligence corresponded to the age norm.
Journal problems of biology and medicine -
Syndromal and nazological structure of pains in children’s backThe causes of back pain in children differ from adults, little studied. The purpose of the surveys was to study the structure of back pain in children using КT and MRТ techniques. Congenital anomalies of the spine, scoliosis, juvenile osteochondrosis, sacroiliata, etc. were found. According to the result, there is a correlation between the patient's age and the presence of concomitant pathology in the form of juvenile osteochondrosis of the spine
Journal problems of biology and medicine -
Complex echographic diagnostics of heart lesions in children with pneumoniaThis work will be based on the results of a comprehensive standard survey of 80 children. Various mani- festations of the pathology of the cardiovascular system, as well as changes in the data of laboratory and func- tional research methods in children of the main group with pneumonia, were accompanied by pronounced gen- eral clinical and local symptoms, which were stopped as the inflammatory process subsided. It should be noted that the functional changes were electrographically expressed in children mainly in the form of sinus tachycar- dia. Complex echographic diagnosis of heart lesions in pneumonia in children is a promising non-invasive method of research, which makes it possible to obtain information about the state of the heart in patients with pneumonia
Journal problems of biology and medicine -
Here are presented the results of conservative treatment of 199 patients wint congenital hip dislocation (hip dysplasia). After 30 years, the results of treatment has been studied in 102 patients. Good results were in 44 patients, satisfactory in 31 and unsatisfactory in 27 patients. The reasons for unsatisfactory results have been identified and methods of their prevention have been recommended. -
Algorithm of early detection, prediction of cardiac-vascular complications in children of early age acute pneumoniaDue to the developed criteria to determine the likelihood of myocarditis in infants with pneumonia, made possible the formation of high-risk groups for adverse outcome of pneumonia. This will increase the likelihood of the development of myocarditis in children and the effectiveness of the therapy, to reduce the incidence of morbidity of acute pneumonia and significantly reduce the number of complications, and thus mortality rate
Journal problems of biology and medicine -
Frequency and structure of visual impairment in children with epilepsyThis article reflects the frequency and structure of visual disorders in children with epilepsy. The study is based on data from a clinical ophthalmological examination of the eyes in 151 children with epilepsy. In the course of the survey, it was found that the frequency of occurrence of the pathology of the eyes was 68.2%. The most common pathology of eyesight in children with epilepsy is established at the age of 1 year to 5 years, which is 47.5%. The correlation interrelation between the duration of the disease and the frequency of epileptic seizures on the development of the pathology of the organs of vision was proved.
Journal problems of biology and medicine -
Cytokine profile of children with the middle ear acute inflammation in acute respiratory disease on the background of treatmentThe aim of the study was to study the cytokine profile in children with acute respirator}' diseases complicated by acute inflammation of the middle ear. Under supervision there were 25 children up to 3 years with acute respiratory diseases complicated by acute otitis media. Thus, the improvement of the clinical status of children, along with the suppression of the level of the proinflammatory cytokine IFNy, was accompanied by the disappearance of signs of inflammation of the middle ear, the improvement of the general condition of the child. However, it should be noted that the change in the level of IL-4 and the violation of the ratio of pro- and anti-inflammatory diseases revealed by us about the presence of a previous immunodeficiency state, which apparently, was manifested by the presence of complications against the background of acute respiratory diseases.
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Efficiency of fargals use in complex treatment of hiv-infected children with acute purified synusitisThe effectiveness of local treatment in inflammatory processes can be significantly improved through the use of scientifically grounded multi-component compositions, taking into account the etiology, pathogenesis, and the difference in the course of the process, where each component directly affects one or another inflammatory factor. Such a drug is FarGALS. Under our supervision were 62 HIV-infected children aged 6 to 16 years who were treated in the children's ENT clinic for acute purulent sinusitis. The use of FarGALS solution in complex treatment and rehabilitation of ENT-organs in HIV-infected children improves the hygienic index by 43%, reduces, up to complete reduction, inflammatory phenomena, enhances the nonspecific protective functions of the mucous membranes of the ENT organs and it is a pronounced positive effect on mucociliary transport of the mucous membrane of the nasal cavity and sinuses.
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Most of the deaths in botulism are due to acute respiratory insufficiency (ODN) before the resuscitation stage. By the severity of the main process the patients were distributed as follows: the patients with severe forms were 7 (23%), medium heavy - 13 (42%) and light-11 (35%). The duration of stay of patients in the hospital amounted to 12,93 ± 0,62 ward-days. The patient is observed in outpatient conditions for 2-3 months after discharge from the stator, if they have acute respirator)' diseases, the patients arc hospitalized because their lung survival is not fully restored. -
According to the modem concept, pathological processes are realized on cell membranes, causing a violation of the structural and functional organization, up to complete destruction. The use of glucocorticoid and cytotoxic therapy in combination with heparin does not guarantee success and lead to complications, especially in children. Consequently, the search for drugs that remove the toxic effects of immunosuppressive therapy continues to be an urgent medical and social problem. What was the reason to study the features of antioxidant therapy in order to optimize the pathogenetic treatment of chronic glomerulonephritis in children. The advantage of therapy with the inclusion of actovegin antioxidant was that parallel to the normalization of malondialdehyde and lysophosphatidylcholine, the other cell membrane fractions increased, apparently due to the ability of aktovegin to reduce the activity of phospholipases. The conducted research will allow to review the tactics of treatment of nephropathy in accordance with the obtained research results, to include in the complex therapy a step-by-step correction of membrane destabilization with Actovegin. In addition, pathogenetic therapy for glomerulonephritis is fraught with complications, ultimately associated with a violation of cellular stability and requires corrective antioxidant therapy. -
The aim of the work was to assess the state of the immune system of children with out-of-hospital pneumonia, comparative analysis of the main parameters of the immune system show ed that the inclusion of an immunocorrec-tor for bronchomunal according to the scheme contributes to a more positive clinical and immunological dynamics, correcting the broken links of immunity. -
Orthodontic state of dental anomalies in children with chronic tonsillitis and bronchitisSocio-mcdical retrospective studies, clinical and dental examinations were conducted among children aged 7-15 years with chronic tonsillitis and chronic bronchitis. During the examinations, children's pathology, somatic pathology and dental anomalies (tooth anatomy and dental anomaly) were assessed using a number of modern measurements, such as frequency, severity and anamalia. An attempt was made to justify the importance of somatic diseases in the development and formation of dental anomalies in comparison with the control group and morphological norms.
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Importance of medical and social factors in etiology of carious and non- сarious diseases of childrenThis article describes scientific research on caries and noncarious diseases in children in recent years, analyzes the social status of parents in certain etiology of caries and non-caries injuries in children and adolescents and their causes.
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Ушбу маколода 126 нафар болаларда йугон ичакнинг хар хил касалликларини ташхислаш учун утказилган виртуал колоноскопия текшириш усулининг натижалари келтирилган. Компьютер томографик виртуал колоноскопия текширув усулининг ташхисий имкониятлари урганилган. Олинган натижаларда болаларда йугон ичак ривожланиши аномалиялари ва касалликлари ташхисида виртуал колоноскопия устуворлиги ва юкори информативлиги курсатилгап. -
In this work there are presented aspects of the postnatal ultrasound diagnosis of the congenital intestinal obstruction in 90 children. On the basis of the literature data and our observations the characteristic echoscopic signs were defined for high, lower intestinal obstruction and in intestinal malrotations in children. There are presented normal dopplcrometric parameters of the blood flow in the superior mesenteric artery in children of the different age groups. -
Epidemiologic and morphologic characteristic of congenital obstruction of small intestine in newborn babiesMorphology of jejunum of experimental animals has identical structural changes with morphology of jejunum in newborn babies with congenital abnormalities of small intestine. Solving of the problems regarding malformations of small intestine in new born babies is actively needed to transfer to the aspect of preventive measures
Journal problems of biology and medicine -
The features of the clinical course and treatment of non-traumatic intracerebral hemorrhages in childrenClinical features of the course of 88 patients with non-traumatic intracerebral hemorrhages (NTIH) were studied. The main causes of the onset of NTIH were late hemolytic disease of newborns (61.4%) and hemorrhages of unexplained etiology (26.1%). The NTIH was more likely located subdural (47.7%) and intracerebral (25.0%), with them children often (38.6%) enter the in-patient department, every third (33.0%) in extremely difficult conditions. The Determination of the regularities of the clinical current non-traumatic intracerebral hemorrhages promotes the identical course of the treatment to early discovery disease and under- taking.
Journal problems of biology and medicine -
Patients and enzymes of antioxidant protection in children with acute nervematic cardio84 children with acute non-rheumatic carditis aged 3 months were examined. up to 3 years. The process-es of LPO are most intensive in patients with hereditary cardiovascular complications: the content of diene conjugates and malonic dialdehyde exceeded by 11.6% and 9.9% of the indices of sick children without anam-nesis. The dependence of the activity of the antioxidant system on genealogical features in children with heredi-tary complications in cardiac pathology was established, catalase activity was lower by 9.4%, and peroxidase was lower by 13.1% than in children without a history of anamnesis
Journal problems of biology and medicine -
Assessment of the treatment efficiency of the distributed appendicular peritonitis in childrenAim of investigation: the analysis of the use of the most commonly used prognostic scales in emergency surgery in patients in two comparison groups on the background of distributed appendicular peritonitis (DAP). Materials and methods: analysis and comparison of the validity of prognostic scales (SOFA, APACHE II, SAPS, MODS, PRISM) was conducted on data from 166 patients. Results: in the main group of patients, the undertaken prcopcrative preparation tactics allows to stabilize the general condition of the patients already on the first day after the operation. At the same time, mortality in the main group varied in the range of 1,8-2,9% (APACHE II - SOFA), and in the comparison group 12,5%-16,7% (APACHE II, MODS - SOFA). Conclusions: the study of the dynamics of indicators on prognostic scales against the background of DAP allows us to identify the most complex groups of patients who need a more serious resource of intensive therapy. When using any of the scales, a linear relationship is found between the number of points and the level of mortality (for example, for SAPS, each ten-point increase corresponds to an increase in mortality of about 10%).
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