108
CLINICAL CRITERIA FOR THE DETECTION OF NON-SPECIFIC
INTERSTITIAL PNEUMONIA
Nikitha Reddy
Student of group 5M55, faculty of General medicine
Scientific Supervisor: N.N. Makhmatmuradova Associate Professor of the
Department of Internal Medicine № 4
Samarkand State Medical University, Uzbekistan
Relevance.
Currently, about two hundred diseases with signs of interstitial lung diseases
have been identified, which is about 20% of all lung diseases, with half of them being of
unclear origin. All this determines the need to optimize diagnostic work in interstitial lung
diseases.
The aim of the study
is to determine the clinical features of nonspecific interstitial
pneumonia.
Material and methods of the study
. The material was a retrospective analysis of the
medical records of 140 patients with non-specific interstitial pneumonia admitted to the
pulmonology department of the Samarkand City Medical Hospital. All patients underwent a
general clinical examination according to ICD-10. The diagnosis was confirmed based on a
combination of clinical and laboratory-instrumental indicators.
Results of the study and discussion
. Patients were conditionally divided into
conditional groups according to the severity of the course of NIP - mild (NIPMC) 16 (11.4%),
moderate (NIPMRC) 59 (42.1%) and severe (NIPSC) 65 (46.4%).
To clarify the clinical picture of NIP in patients, the results of an objective examination
of the lungs, percussion and auscultation were taken into account. The characteristics of
patients with NIP, their anamnesis, complaints and results of an objective examination were
determined: humidity in living quarters, the presence of rheumatic diseases; unproductive
cough and dyspnea; During the disease, weight loss is noted, changes in the phalanges of the
fingers according to the type of "drumsticks", changes in the nails according to the type of
"watch glasses"; with percussion - tympanic and box sound in the lungs; increased bronchial
breathing, hard and weak vesicular breathing. With auscultation in the lungs - crepitant, small
and medium bubbling moist rales.
The clinical picture continued to be different: under the "mask" of acute respiratory
infections - 8%, under the "mask" of acute bronchitis - 13%, under the "mask" of chronic
bronchitis - 23%, under the "mask" of sluggish pneumonia - 27%, under the "mask" of acute
pneumonia - 29%. The main clinical manifestations are cough without sputum - 86%,
shortness of breath with minor physical exertion - 78%, subfebrile temperature - 41%.
Auscultatory data are scarce. Increased bronchial breathing was noted - 75% and weakening
of vesicular breathing - 64%. Crepitating wheezing - 67%, moist small and medium bubbling
rales with - 41%.
Laboratory data: complete blood count - leukocytosis 9-10 (10x9/l), left shift in the
leukocyte formula 15-16%, erythrocyte sedimentation rate - 14-17 mm/h. Immunological
109
study of the qualitative composition of T- and B-lymphocytes revealed a decrease in the
lymphocyte subpopulation - 17-18%. The radiographic picture was as follows: obstructive
bronchitis - 47%, hilar pneumonia - 35%, bilateral pneumonia - 18%. Computed tomography
revealed: deforming bronchitis changes with pneumofibrosis - 31%, ground glass changes -
37%, peribronchial infiltration with focal compaction of lung tissue - 32%.
Changes in the function of external respiration during spirography were recorded as
follows: restrictive disorders - 42%, mixed disorders - 34%, mixed type with a predominance
of restrictive disorders - 24%. During hospitalization, clinical and spirographic signs of
bronchial obstruction were not detected, however, spirographically, pronounced restrictive
disorders - volumetric indicators - were detected.
Conclusion
. Thus, non-specific interstitial pneumonia is characterized by a diverse
clinical course. The clinical course of the pathology largely depends on the state of reactivity
and severity of the disease of the div. At the same time, the main clinical manifestation of
the disease in 86% was cough with sputum, and 34% had persistent recurrent episodes. Many
patients have decreased immunity.
REFERENCES:
1.
Шахизирова, Ирода, and Гулчехра Хамраева. "Clinical Manifestations of Post-
Covid Syndrome among Children." in Library 3.3 (2023).
2.
Хомова, Н. А., В. М. Коломиец, and Ф. К. Ташпулатова. "Приверженность к
лечению
больных
туберкулезом
как
фактор
риска
снижения
его
эффективности." Университетская наука: взгляд в будущее. 2020.
3.
Agzamova, Shoira. "Value of heart rate variability parameters in prognosis of
intrauterine infection of infants with cytomegalovirus." Medical Health and Science
Journal 4.4 (2010): 24-29.
4.
Агзамова, Ш. А., and Ф. Т. Махкамова. "Влияние вирусной инфекции у
беременных на жизнеспособность новорожденных." Детская больница 3 (2014): 22-25.
5.
Агзамова, Ш. "Артериальная гипертензия у детей: Полиморфизм BsmI
(rs1544410) гена VDR и витамина D." Актуальные вопросы практической
педиатрии 1.1 (2023): 17-19.
